Since their discovery and subsequent development into laboratory tools, CRISPR-Cas systems have revolutionized the science of gene editing and their possible applications continue to expand, from basic research to potentially groundbreaking medical and commercial uses.
Led by a distinguished team of editors, CRISPR: Biology and Applications explores the subject matter needed to delve into this fascinating area. This comprehensive text presents the diversity of CRISPR-Cas systems, the underlying biology of these systems, and CRISPR-based technologies and applications. Topics covered include:
- Classification and molecular mechanisms of CRISPR-Cas systems
- CRISPR-Cas evolution, regulation, expression, and function
- Uses for gene editing and modulation of gene expression
- CRISPR-based antimicrobials and phage resistance for medical and industrial purposes
Written by internationally renowned authors, CRISPR: Biology and Applications serves as both an introductory guide for those new to the field and a ready reference for seasoned researchers whose work touches this evolving and headline-making science.
