"All in all, this sixth edition of Fitzpatrick's Dermatology in General Medicine is the premier textbook of dermatology, a bargain if there ever was one." -Michael B. Brodin, MD
Journal of the American Medical Association
NOW IN A STATE-OF-THE-ART NEW EDITION
The up-to-the-minute sixth edition of the world-renowned Fitz
*Encyclopedic in its scope with 280 definitive chapters in 37 sections covering every aspect, every problem, every treatment strategy related to human skin
*Packed with 2,000 full-color photographs of the highest quality -- and hundreds of topic-clarifying line drawings
*Presents the expertise of over 300 world-class contributors 50 new to this edition
*Reorganized and expanded, with updated content throughout
*Features the definitive chapter on smallpox and complications of vaccination
*Includes 10 timely new chapters on topics ranging from photoimmunology to retinoids and botox
Reorganized and edited for total clarity and ease of use, the sixth editions coverage of dermatologic conditions and systemic diseases presenting with skin manifestations provides for each disorder:
*Historical Aspects of the Condition
*Epidemiology
*Clinical Manifestations
*Laboratory Findings
*Pathology
*Treatment and Prognosis
The sixth edition of Fitz gives you the most timely, authoritative, and comprehensive guide to the entire spectrum of dermatologic science, diagnosis, treatment, and management.
Recenzijas
It has been said that dermatology is the most inclusive specialty because it deals not only with the skin but also with everything that the skin contains and touches. There's some truth to that. For instance, where else can you find the editors of a medical textbook, as in Fitzpatrick's Dermatology in General Medicine, waxing proudly in the preface about including fresh material on anthrax, smallpox, and Botox? In other words, the field considers its domain to range from the war on terrorism to our narcissistic culture. Happily, the Botox chapter does not include tips on how to throw a "Botox party." There is also a new chapter on "Evidence-Based Dermatology." I must admit that when I first heard of the evidence-based approach, I wasn't much impressed with its novelty, seeming to remember at least one old-timer who made a comment about experiment being treacherous and judgment difficult (Hippocrates). But the author does a good job of defending the system, and in an honest self-referential bit of criticism of textbooks, he points out that most tend to "reflect the biases and shortcomings of the experts who write them," are about 2 years out of date by publication, and are "narrative reviews that do not consider the quality of the evidence reported." Evidence itself, of course, is as indisputably wholesome as apple pie--it's how you interpret the evidence that matters. This edition remains heavily invested in basic science, which is becoming daily more of a misnomer as skin biology reveals an ever increasing complexity. The first part, almost 15%, is given over to anatomy, physiology, immunology, molecular biology, and so forth, and there's much more interspersed throughout the clinical chapters. These chapters have shown the most profound changes over time, with progressive improvement at each turn. Whereas the first edition relegated color clinical photographs to a relatively thin "atlas" section, this edition features them on seemingly every page. Color abounds, and the quality of the illustrations is excellent. Indeed, the difference between the first and latest edition is so great that you'd never guess at the lineage if you did not look at the titles. With all the new material, I was astonished to discover that something unheard of had apparently occurred in medical publishing: the sixth edition is shorter than the fifth! And not by just a little: hundreds of pages have evaporated. I compared typefaces, considered a gross error in the pagination, had a colleague check my eyesight, and finally contacted the senior editor, who gave me the lowdown: they did it on purpose. Having decided that the book had grown "too long, too heavy, too redundant," a 2-year effort was launched in which 10% was cut by "rigid editing, eliminating as much duplication as possible, cutting long, long lists of references." Another improvement was making both volumes roughly equal in size (the considerable inequality of which had always annoyed me) and using a thinner but ample stock paper. The overall weight has been reduced from 22 lb to a more portable 17 lb. All in all, this sixth edition of Fitzpatrick's Dermatology in General Medicine is the premier textbook of dermatology, a bargain if there ever was one, and a blessing for those of us with derangements in our rotator cuffs. Michael B. Brodin, MD Monroe, NY Journal of American Medical Association 20040121 "The book is well formatted and easy to read. It summarizes all the crucial recent studies that have a major impact in our approach to treatment of hypertension in diabetes mellitus." "4 stars" Doody's 20031003
PART ONE IntroductionSection 1 General Considerations1. Where Have We Come From? Karl Holubar and Stella Fatovi¿-Feren¿i¿2. The Epidemiology and Burden of Skin Disease Martin A. Weinstock and Mary-Margaret ChrenSection 2 Clinical-Pathologic Correlations of Skin Lesions: Approach to Diagnosis
3. The Structure of Skin Lesions and Fundamentals of Diagnosis Margaret I. Stewart, Jeffrey D. Bernhard, Thomas G. Cropley, and Thomas B. Fitzpatrick4. Basic Pathologic Reactions of the Skin Klaus Wolff, Abdul-Ghani Kibbi, and Martin C. Mihm, Jr.PART TWO Biology and Development of SkinSection 3 Structure and Development of Skin
5. Genetics in Relation to the Skin Lowell A. Goldsmith and Ervin H. Epstein, Jr.6. The Structure and Development of Skin David H. Chu, Anne R. Haake, Karen Holbrook, and Cynthia A. LoomisSection 4 Biology and Function of Epidermis and Appendages
7. Epidermal Cell Kinetics, Epidermal Differentiation, and Keratinization Arash Kimyai-Asadi, Ming H. Jih, and Irwin M. Freedberg8. Biology of Eccrine and Apocrine Sweat Glands Lowell A. Goldsmith9. Skin As an Organ of Protection Peter M. Elias, Kenneth R. Feingold, and Joachim W. Fluhr10. Thermoregulation C. Bruce Wenger11. Biology of Melanocytes Ruth Halaban, Daniel N. Hebert, and David E. Fisher12. Biology of Hair Follicles Robert M. Lavker, Arthur Bertolino, Irwin M. Freedberg, and Tung-Tien Sun13. Biology of Nails Antonella Tosti and Bianca Maria PiracciniSection 5 Biology of Extracellular Matrix, Blood Vessels, and Nerves14. CollagenJouni Uitto, Leena Pulkkinen, and Mon-Li Chu15. Elastic FibersJouni Uitto and Mon-Li Chu16. Basement MembranesLeena Bruckner-Tuderman17. The Role of Extracellular Matrix Metalloproteinases in Connective Tissue RemodelingJo L. Seltzer and Arthur Z. Eisen18. Proteoglycans and Glycosaminoglycans of SkinRichard L. Gallo and Janet M. Trowbridge19. EndotheliumPeter Petzelbauer, Jeffrey S. Schechner, and Jordan S. Pober20. Neurobiology of the Skin Franz J. Legat, Cheryl A. Armstrong, Thomas Scholzen, John E. Olerud, Nigel W. Bunnett, Thomas A. Luger, and John C. Ansel21. Mechanisms of Cutaneous Wound RepairVincent FalangaSection 6 Cellular and Molecular Biology of Inflammation, Repair, and Carcinogenesis22. Innate Immunity and the Skin Jenny Kim and Robert L. Modlin23. The Skin: An Immunologic BarrierGeorg Stingl, Dieter Maurer, Conrad Hauser, and Klaus Wolff24. Influence of the HLA System on Disease SusceptibilityMadeleine Duvic25. Immunoglobulin Structure and FunctionLela A. Lee26. CytokinesIfor R. Williams, Benjamin E. Rich, and Thomas S. Kupper27. ChemokinesSam T. Hwang28. Lymphocytes Robert L. Modlin29. Regulation of the Production and Activation of NeutrophilsShireen V. Guide and Steven M. Holland30. Regulation of the Production and Activation of EosinophilsAdrienne Rencic and Lisa A. Beck31. Regulation of the Production and Activation of BasophilsJohn T. Schroeder32. The Molecular and Cellular Biology of the Mast CellFred H. Hsieh, Clifton O. Bingham, III, and K. Frank Austen33. Human Complement SystemIrma Gigli34. EicosanoidsAlice P. Pentland35. Cellular Hypersensitivity and DNA RepairKenneth H. Kraemer36. Carcinogenesis: ChemicalAndrzej Dlugosz and Stuart H. Yuspa37. Oncogenes and Viral CarcinogenesisDouglas R. Lowy38. Carcinogenesis: Ultraviolet RadiationMargaret L. Kripke and Honnavara N. Ananthaswamy39. Photoimmunology Richard D. GransteinPART THREE Disorders Presenting in the Skin and Mucous MembranesSection 7 Noncutaneous Manifestations of Skin Diseases40. Psychological Aspects of Skin DiseaseThomas W. Koenig, Sylvia Garnis-Jones, Adrienne Rencic, and Francisco A. Tausk41. Pathophysiology and Clinical Aspects of PruritusMalcolm W. GreavesSection 8 Epidermis: Disorders of Persistent Inflammation, Cell Kinetics, and Differentiation42. PsoriasisEnno Christophers and Ulrich Mrowietz43. Psoriatic ArthritisRobert Winchester44. Exfoliative DermatitisMing H. Jih, Arash Kimyai-Asadi, and Irwin M. Freedberg45. Pityriasis Rubra PilarisLowell A. Goldsmith and Howard P. Baden46. Pityriasis RoseaAlf Björnberg and Eva Tegner47. ParapsoriasisGary S. Wood and Chung-Hong Hu48. Pityriasis LichenoidesMazen S. Daoud and Mark R. Pittelkow49. Lichen PlanusMazen S. Daoud and Mark R. Pittelkow50. Lichen NitidusMazen S. Daoud and Mark R. Pittelkow51. Ichthyosiform DermatosesJohn J. DiGiovanna52. The Inherited Keratodermas of Palms and SolesHoward P. Stevens, David P. Kelsell, and Irene M. Leigh53. Ectodermal DysplasiasVirginia P. Sybert54. Darier-White Disease (Keratosis Follicularis) and Acrokeratosis VerruciformisLowell A. Goldsmith and Howard P. Baden55. Transient Acantholytic Dermatosis (Grover Disease)Peter J. Heenan and Christopher J. Quirk56. PorokeratosisElisabeth Ch. Wolff-Schreiner57. Kyrle Disease and Other Perforating DisordersElisabeth Ch. Wolff-SchreinerSection 9 Epidermis: Disorders of Epidermal Cohesion—Vesicular and Bullous Disorders58. Erythema Multiforme, Stevens-Johnson Syndrome, and Toxic Epidermal NecrolysisPeter O. Fritsch and Ramon Ruiz-Maldonado59. PemphigusJohn R. Stanley60. Paraneoplastic PemphigusGrant J. Anhalt and H. Carlos Nousari61. Bullous PemphigoidJohn R. Stanley62. Cicatricial PemphigoidKim B. Yancey63. Linear IgA Dermatosis and Chronic Bullous Disease of ChildhoodCaroline L. Rao and Russell P. Hall, III64. Pemphigoid Gestationis (Herpes Gestationis)Stephen I. Katz65. Inherited Epidermolysis BullosaM. Peter Marinkovich, Paul A. Khavari, G. Scott Herron, and Eugene A. Bauer66. Epidermolysis Bullosa AcquisitaDavid T. Woodley, Mei Chen, W. Ray Gammon, and Robert A. Briggaman67. Dermatitis HerpetiformisStephen I. Katz68. Familial Benign Pemphigus (Hailey-Hailey Disease)Robin A.C. Graham-Brown69. Subcorneal Pustular Dermatosis (Sneddon-Wilkinson Disease)Herbert Hönigsmann, Franz Trautinger, and Klaus Wolff70. Pustular Eruptions of Palms and SolesEnno Christophers and Ulrich MrowietzSection 10 Disorders of Epidermal Appendages and Related Disorders
71. Hair DisordersElise A. Olsen72. NailsRobert Baran and Antonella Tosti73. Diseases of the Sebaceous GlandsDiane M. Thiboutot and John S. Strauss74. RosaceaGerd Plewig and Thomas Jansen75. Perioral DermatitisR. Marks76. Disorders of the Eccrine Sweat GlandsLowell A. Goldsmith77. Disorders of the Apocrine Sweat GlandsMazen S. Daoud and Charles H. Dicken78. Follicular Syndromes with Inflammation and AtrophyPeter O. FritschSection 11 Epidermal and Appendageal Tumors
79. Epithelial Precancerous LesionsKarynne O. Duncan and David J. Leffell80. Squamous Cell CarcinomaDouglas Grossman and David J. Leffell81. Basal Cell CarcinomaJohn A. Carucci and David J. Leffell82. Basal Cell Nevus SyndromeErvin H. Epstein, Jr.83. KeratoacanthomaLorenzo Cerroni and Helmut Kerl84. Benign Epithelial TumorsShane G. Silver and Vincent C.Y. Ho85. Appendage Tumors of the Skin Steven Kaddu and Helmut Kerl86. Cutaneous Neuroendocrine Carcinoma: Merkel Cell CarcinomaHelmut Kerl and Rainer Hofmann-Wellenhof87. Mammary and Extramammary Pagets DiseaseS.M. ConnollySection 12 Disorders of Melanocytes88. Normal Skin Color and General Considerations of Pigmentary DisordersThomas B. Fitzpatrick and Jean-Paul Ortonne89. AlbinismPhilippe Bahadoran, Jean-Paul Ortonne, Richard A. King, and William S. Oetting90. Hypomelanoses and HypermelanosesJean-Paul Ortonne, Philippe Bahadoran, Thomas B. Fitzpatrick, David B. Mosher, and Yoshiaki Hori91. Benign Hyperplasias and Neoplasias of MelanocytesJames M. Grichnik, Arthur R. Rhodes, and Arthur J. Sober92. Atypical Melanocytic NeviHensin Tsao and Arthur J. Sober93. Neoplasms: Cutaneous MelanomaRichard G.B. Langley, Raymond L. Barnhill, Martin C. Mihm, Jr., Thomas B. Fitzpatrick, and Arthur J. SoberSection 13 Inflammatory and Neoplastic Disorders of the Dermis94. Acute Febrile Neutrophilic Dermatosis (Sweets Syndrome)Herbert Hönigsmann, Philip R. Cohen, and Klaus Wolff95. Erythema Elevatum DiutinumStephen I. Katz96. Eosinophils in Cutaneous DiseasesKristin M. Leiferman, Margot S. Peters, and Gerald J. Gleich97. Granuloma FacialeWalter H.C. Burgdorf98. Pyoderma GangrenosumKlaus Wolff and Georg Stingl
99. Erythema Annulare Centrifugum and Other Figurate ErythemasWalter H.C. Burgdorf100. Granuloma AnnulareMark V. Dahl101. Malignant Atrophic Papulosis (Degos Disease)Louis Dubertret102. Fibrous Lesions of Dermis and Soft TissueChristopher R. Shea and Victor G. Prieto103. Vascular Anomalies and Tumors of Skin and Subcutaneous TissuesSuzanne Virnelli Grevelink and John Butler Mulliken104. Kaposis SarcomaKlemens Rappersberger, Georg Stingl, and Klaus Wolff105. Anetoderma and Other Atrophic Disorders of the SkinWalter H.C. Burgdorf106. Ainhum and PseudoainhumWalter H.C. Burgdorf107. Neoplasias and Hyperplasias of Neural and Muscular OriginSteffen Albrecht108. Acquired Perforating DisordersMark LebwohlSection 14 Disorders of Subcutaneous Tissue
109. PanniculitisMichael J. Camilleri and W.P. Daniel Su110. LipodystrophyErvin H. Epstein, Jr.111. Neoplasms of the Subcutaneous FatKarl H. AndersSection 15 Disorders of the Mucocutaneous Integument112. Biology and Pathology of the Oral MucosaJonathan A. Ship, Joan Phelan, and A. Ross Kerr113. Diseases and Disorders of the Male GenitaliaRichard Allen Johnson114. Diseases and Disorders of the Anogenitalia of FemalesLibby EdwardsSection 16 Cutaneous Changes in Disorders of Altered Reactivity115. Genetic Immunodeficiency DiseasesAmy S. Paller116. Urticaria and AngioedemaNicholas A. Soter and Allen P. Kaplan117. Angioedema Associated with Complement AbnormalitiesIrma Gigli and Fred S. Rosen118. Graft-versus-Host DiseaseThomas D. Horn119. Mucocutaneous Manifestations of the Non-HIV-Infected Immunosuppressed HostAndrew Blauvelt120. Allergic Contact DermatitisDonald V. Belsito121. Autosensitization Dermatitis122. Atopic Dermatitis (Atopic Eczema)Donald Y.M. Leung, Lawrence F. Eichenfield, and Mark Boguniewicz123. Nummular Eczema and Lichen Simplex Chronicus/Prurigo NodularisNicholas A. Soter124. Seborrheic DermatitisGerd Plewig and Thomas Jansen125. Vesicular Palmoplantar EczemaAlexa Boer KimballSection 17 Skin Changes Due to Mechanical and Physical Factors126. Cold InjuriesGérald Piérard, Isabelle Fumal, and Claudine Piérard-Franchimont127. Evaluation and Management of the Thermally Injured PatientRobert Sheridan128. Radiobiology and Radiotherapy of Skin DiseasesFrederick D. Malkinson and Renato G. Panizzon129. Skin Problems in Amputees and OstomatesCalum C. Lyon and Michael H. Beck130. Corns and CallusesThomas M. DeLauro131. Sports DermatologyDirk M. Elston132. Decubitus (Pressure) Ulcers and Venous UlcersJoel M. Gelfand and David J. MargolisSection 18 Photomedicine133. Photophysics, Photochemistry, and PhotobiologyIrene E. Kochevar and Charles R. Taylor134. Acute and Chronic Effects of Ultraviolet Radiation on the SkinSusan L. Walker, John L.M. Hawk, and Antony R. Young135. Abnormal Responses to Ultraviolet Radiation: Idiopathic, Probably Immunologic, and PhotoexacerbatedJohn L.M. Hawk, Paul G. Norris, and Herbert Hönigsmann136. Abnormal Responses to Ultraviolet Radiation: Photosensitivity Induced by Exogenous AgentsHenry W. LimSection 19 Disorders Due to Drugs and Chemical Agents137. Occupational Skin DiseaseJames S. Taylor and Apra Sood138. Cutaneous Reactions to DrugsNeil H. Shear, Sandra R. Knowles, John R. Sullivan, and Lori Shapiro139. Mucocutaneous Complications of Antineoplastic TherapyJames E. Fitzpatrick140. Cutaneous Reactions to Cytokines and Growth FactorsMaria L. Chanco Turner141. Cutaneous Manifestations of Drug AbuseMiguel R. SanchezPART FOUR Dermatology and MedicineSection 20 Skin Changes across the Span of Life142. Skin Changes and Diseases in PregnancyThomas J. Lawley and Kim B. Yancey143. Neonatal, Pediatric, and Adolescent DermatologyMary Wu Chang and Seth J. Orlow144. Aging of SkinMina Yaar and Barbara A. GilchrestSection 21 Skin Lesions in Nutritional, Metabolic, and Heritable Disorders145. Cutaneous Changes in Nutritional DiseaseDavid S. Nieves and Lowell A. Goldsmith146. Acrodermatitis Enteropathica and Other Zinc-Deficiency DisordersKenneth H. Neldner147. Cutaneous Changes in Errors of Amino Acid Metabolism: Tyrosinemia II, Phenylketonuria, Argininosuccinic Aciduria, and AlkaptonuriaLowell A. Goldsmith148. Amyloidosis of the SkinStephen Michael Breathnach149. The PorphyriasDavid R. Bickers and Jorge Frank150. Xanthomatoses and Lipoprotein DisordersLowell A. Goldsmith151. Fabry Disease: ¿-Galactosidase A Deficiency (Angiokeratoma Corporis Diffusum Universale)Robert J. Desnick and Maryam Banikazemi152. Lipoid ProteinosisCh. M. Lapière153. Cutaneous Mineralization and OssificationJohn S. Walsh and Janet A. Fairley154. Heritable Disorders of Connective Tissue with Skin ChangesRichard J. Wenstrup and Huiquan Zhao155. Heritable Diseases with Increased Sensitivity to Cellular InjuryKenneth H. KraemerSection 22 Skin Manifestations of Bone Marrow or Blood Element Disorders156. Hematologic DiseasesWarren W. Piette157. Cutaneous T Cell LymphomasJo-Ann Latkowski and Peter W. Heald158. Other Systemic Lymphomas with Skin InfiltrationWolfram Sterry and J. Marcus Muche159. Inflammatory Diseases That Simulate Lymphomas: Cutaneous PseudolymphomasGary S. Wood160. Langerhans Cell HistiocytosisRuggero Caputo161. Cutaneous Nonhistiocytoses XRuggero Caputo162. Multicentric ReticulohistiocytosisKarl Holubar163. The Mastocytosis SyndromeDean D. MetcalfeSection 23 Skin Manifestations of Gastrointestinal and Renal Disorders164. The Skin and Disorders of the Alimentary Tract and the Hepatobiliary SystemGraham A. Johnston and Robin A.C. Graham-Brown165. Cutaneous Changes in Renal DisordersSusan Sweeney and Thomas G. CropleySection 24 Skin Manifestations of Disorders of the Cardiovascular and Pulmonary Systems166. Cutaneous Aspects of Cardiopulmonary DiseaseAndrew G. Franks, Jr., and Victoria P. Werth167. Cutaneous Changes in Peripheral Vascular DiseaseJay D. Coffman and Robert T. EberhardtSection 25 Skin Manifestations of Alterations and Disorders of the Endocrine System168. Diabetes MellitusJennifer L. Bub and John E. Olerud169. Cutaneous Manifestations of Other Endocrine DiseasesJanie M. Leonhardt and Warren R. Heymann170. Cutaneous Changes in the Flushing Disorders and the Carcinoid SyndromeEva A. Hurst and Michael P. HeffernanSection 26 Skin Manifestations of Rheumatologic Multisystem Diseases171. Lupus ErythematosusMelissa I. Costner and Richard D. Sontheimer172. DermatomyositisRichard D. Sontheimer and Melissa I. Costner173. SclerodermaBenjamin D. Yu and Arthur Z. Eisen174. Systemic Necrotizing ArteritisBrian F. Mandell and Gary S. Hoffman175. Cutaneous Necrotizing VenulitisNicholas A. Soter176. Pigmented Purpuric DermatosesTheresa Schroeder177. Cryoglobulinemia and CryofibrinogenemiaLynn A. Cornelius and Thomas J. Lawley178. Relapsing PolychondritisStephen I. Katz179. Rheumatoid Arthritis, Rheumatic Fever, and GoutCarlin B. Hollar and Joseph L. Jorizzo180. Sjögrens SyndromeH. Carlos Nousari and Thomas T. Provost181. Raynauds PhenomenonJohn H. Klippel182. Reiters SyndromeRobert WinchesterSection 27 Skin Manifestations of Diseases in Other Organ Systems183. SarcoidosisIrwin M. Braverman184. Cutaneous Manifestations of Internal Malignant Disease: Cutaneous Paraneoplastic SyndromesDavid I. McLean and Harley A. Haynes185. Acanthosis NigricansKaren R. Houpt and Ponciano D. Cruz, Jr.186. ScleredemaRaul Fleischmajer187. Papular MucinosisRaul Fleischmajer188. Neurocutaneous DiseasesRudolf Happle189. Tuberous Sclerosis ComplexAmy S. Paller and Lowell A. Goldsmith190. The NeurofibromatosesEniko K. Pivnick and Vincent M. Riccardi191. Ataxia-TelangiectasiaAmy S. Paller192. Behçets DiseaseRachel A. Garton and Joseph L. JorizzoPART FIVE Diseases Due to Microbial Agents, Infestations, Bites, and StingsSection 28 Bacterial Diseases with Cutaneous Involvement193. General Considerations of Bacterial DiseasesMorton N. Swartz and Arnold N. Weinberg194. Pyodermas: Staphylococcus Aureus, Streptococcus, and Other Gram-Positive BacteriaPeter K. Lee, Matthew T. Zipoli, Arnold N. Weinberg, Morton N. Swartz, and Richard A. Johnson195. Staphylococcal Scalded Skin SyndromeSteven D. Resnick and Peter M. Elias196. Soft Tissue Infections: Erysipelas, Cellulitis, Gangrenous Cellulitis, and MyonecrosisArnold N. Weinberg, Morton N. Swartz, Hensin Tsao, and Richard A. Johnson197. Gram-Negative Coccal and Bacillary InfectionsArnold N. Weinberg and Morton N. Swartz198. BartonellosisTimothy G. Berger and Francisco Bravo199. Miscellaneous Bacterial Infections with Cutaneous ManifestionsMorton N. Swartz and Arnold N. Weinberg200. Tuberculosis and Other Mycobacterial InfectionsGerhard Tappeiner and Klaus Wolff201. Actinomycosis, Nocardiosis, and ActinomycetomaMauricio Goihman-Yahr, Michael M. McNeil, and June M. Brown
202. LeprosyThomas H. Rea and Robert L. Modlin203. Lyme BorreliosisEva Åsbrink and Anders Hovmark204. Kawasaki SyndromeDonald Y.M. Leung and Anne W. LuckySection 29 Fungal Diseases with Cutaneous Involvement205. Superficial Fungal Infection: Dermatophytosis, Onychomycosis, Tinea Nigra, PiedraMichael M. Nelson, Ann G. Martin, and Michael P. Heffernan206. Yeast Infections: Candidiasis, Pityriasis (Tinea) VersicolorAlison S. Klenk, Ann G. Martin, and Michael P. Heffernan207. Deep Fungal InfectionsR.J. HaySection 30 Viral and Rickettsial Diseases208. Viral Diseases: General ConsiderationsDouglas R. Lowy209. Rubella (German Measles)Stephen E. Gellis210. MeaslesLouis Z. Cooper211. Hand-Foot-and-Mouth DiseaseRaphael Dolin212. HerpanginaDavid A. Sirois213. Erythema Infectiosum and Parvovirus B19 InfectionKaren Wiss214. Herpes SimplexAdriana R. Marques and Stephen E. Straus215. Varicella and Herpes ZosterStephen E. Straus, Kenneth E. Schmader, and Michael N. Oxman216. Cytomegalovirus InfectionFrancesco Drago and Alfredo Rebora217. Epstein-Barr Virus InfectionsJeffrey I. Cohen218. Human Herpesvirus 6 and 7 Infections and Exanthem Subitum (Roseola Infantum or Sixth Disease)Sandy Tsao219. Smallpox and Complications of Smallpox VaccinationVincent A. Fulginiti220. Orf (Contagious Pustular Dermatitis, Contagious Ecthyma)Renee R. Snyder and Dayna G. Diven221. Molluscum ContagiosumDouglas R. Lowy and Elliot J. Androphy222. Milkers NodulesDouglas R. Lowy223. WartsDouglas R. Lowy and Elliot J. Androphy224. Human Retroviral Disease: Human T-Lymphotropic VirusesErwin Tschachler, Marvin S. Reitz, Jr., and Genoveffa Franchini225. Cutaneous Manifestations of Human Immunodeficiency Virus DiseaseRichard Allen Johnson226. Prions and the SkinJohannes Pammer and Erwin Tschachler227. The Rickettsioses and EhrlichiosesJustin J. Green and Warren R. HeymannSection 31 Sexually Transmitted Diseases228. SyphilisMiguel R. Sanchez229. Endemic (Nonvenereal) TreponematosisMiguel R. Sanchez230. ChancroidStephan Lautenschlager and Alfred R. Eichmann231. Lymphogranuloma VenereumRichard Rothenberg232. Granuloma InguinaleRichard Rothenberg233. GonorrheaDavid S. Feingold and Claire P. Mansur234. Other Venereal DiseasesAlfred R. Eichmann and Stephan LautenschlagerSection 32 Infestations235. Leishmaniasis and Other Protozoan InfectionsSidney N. Klaus, Shoshana Frankenburg, and A. Damian Dhar236. Cysticercosis and Other Helminthic InfectionsLeslie C. Lucchina and Mary E. WilsonSection 33 Bites and Stings237. Bites and Stings of Terrestrial and Aquatic LifeMark Jordan Scharf and Jennifer Susan Daly238. Scabies and PediculosisStephen P. Stone239. Arthropod Bites and StingsDavid C. Wilson, Michael L. Smith, and Lloyd E. King, Jr.PART SIX TherapeuticsSection 34 Evidence-Based Dermatology240. Evidence-Based DermatologyMichael Bigby and Moyses SzkloSection 35 Topical Therapy241. Pharmacokinetics and Topical Applications of DrugsHans Schaefer, Thomas E. Redelmeier, and Gerhard J. Nohynek242. Principles of Topical TherapyBruce E. Strober, Ken Washenik, and Jerome L. Shupack243. Topical GlucocorticoidsIsabel C. Valencia and Francisco A. Kerdel244. Topical RetinoidsSewon Kang and John J. Voorhees245. Topical AntibioticsMark W. Bonner, Paul M. Benson, and William D. James246. Topical Antifungal AgentsJames E. Fitzpatrick247. Sun Protective Agents: Formulations, Effects, and Side EffectsFrancis P. Gasparro, Douglas Brown, Brian L. Diffey, John S. Knowland, and Vivienne Reeve248. Keratolytic AgentsHoward P. Baden and Lynn A. Baden249. Topical Cytotoxic AgentsLesley Clark-Loeser, Ken Washenik, and Jerome L. Shupack250. Topical ImmunomodulatorsRobert Sidbury and Jon M. Hanifin251. Other Topical MedicationsAdam I. Rubin, Nicole LaNatra, and Matthew J. Stiller252. Cosmetics and Skin Care in Dermatologic PracticePatricia G. Engasser and Howard I. MaibachSection 36 Systemic Therapy253. Systemic GlucocorticoidsVictoria P. Werth254. SulfonesStephen I. Katz255. AminoquinolinesJeffrey R. LaDuca and Anthony A. Gaspari256. Cytotoxic and Antimetabolic AgentsChristopher T. Cassetty, Jerome L. Shupack, and Ken Washenik257. The RetinoidsStéphane Kuenzli and Jean-Hilaire Saurat258. AntihistaminesNicholas A. Soter259. Overview of AntibioticsJan V. Hirschmann260. Antiviral DrugsRaphael Dolin261. Oral Antifungal AgentsNellie Konnikov and Helen Raynham262. Immunosuppressive and Immunomodulatory DrugsH. Carlos Nousari and Grant J. Anhalt263. Immunobiologicals in DermatologyJames G. Krueger and Alice B. Gottlieb264. ThalidomideGerhard Tappeiner and Klaus Wolff265. Therapeutic Photomedicine: PhototherapyJean Krutmann and Akimichi Morita266. Photochemotherapy and Photodynamic TherapyHerbert Hönigsmann, Rolf-Markus Szeimies, Robert Knobler, Thomas B. Fitzpatrick, Madhukar A. Pathak, and Klaus Wolff267. Lasers in DermatologyGraeme M. Lipper and R. Rox AndersonSection 37 Surgery in Dermatology268. Dermatologic Surgery: Introduction and ApproachJune K. Robinson and George J. Hruza269. Skin Resurfacing: Chemical PeelsHarold J. Brody270. Skin Resurfacing: DermabrasionChristopher B. Harmon and John M. Yarborough, Jr.271. Skin Resurfacing: LaserGeorge J. Hruza, Jeffrey S. Dover, and Kenneth A. Arndt272. Wound DressingsMichelle M. Choucair, Ysabel M. Bello, and Tania J. Philips273. Treatment of Varicose and Telangiectatic VeinsRobert A. Weiss and Margaret A. Weiss274. Tumescent LiposuctionRhoda S. Narins, Arnold William Klein, and Jeffrey A. Klein275. Substances for Soft-Tissue AugmentationArnold William Klein276. Botulinum ToxinRichard G. Glogau277. Hair Transplantation and Alopecia ReductionWalter Unger and Robert Unger278. CryosurgeryGloria F. Graham, K. Andrew Cerveny, Jr., and James SanFilippo279. Mohs Micrographic SurgeryKen K. Lee and Neil A. Swanson280. Nail SurgeryRobert Baran Index
George Miller MacKee Professor and Chairman The Ronald O. Perelman Department of Dermatology New York University New York, New York
Emma Showman Professor of Dermatology Program Director, Chief Emeritus Washington University School of Medicine St. Louis , MO
Professor and Chairman Emeritus, Department of Dermatology, The University of Vienna Medical School, Vienna General Hospital, Vienna, Austria.
AstraZeneca Professor of Respiratory and Inflammatory Diseases Harvard Medical School Brigham and Women's Hospital Boston, MA
Professor of Dermatology, University of North Carolina, Chapel Hill, NC Dean Emeritus, University of Rochester School of Medicine and Dentistry, Rochester, NY
Director, National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institutes of Health Bethesda, Maryland