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Nutraceuticals in Brain Health and Beyond [Mīkstie vāki]

Edited by (Nutriconnect, Sydney, Australia; Food Nutrition Partners, New Zealand; Trigonella Labs Pty Ltd Australia; Australian ambassador of the Global Harmonization Initiative.)
  • Formāts: Paperback / softback, 476 pages, height x width: 276x216 mm, weight: 1270 g
  • Izdošanas datums: 13-Nov-2020
  • Izdevniecība: Academic Press Inc
  • ISBN-10: 0128205938
  • ISBN-13: 9780128205938
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  • Cena: 180,86 €
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  • Formāts: Paperback / softback, 476 pages, height x width: 276x216 mm, weight: 1270 g
  • Izdošanas datums: 13-Nov-2020
  • Izdevniecība: Academic Press Inc
  • ISBN-10: 0128205938
  • ISBN-13: 9780128205938
Citas grāmatas par šo tēmu:

Nutraceuticals in Brain Health and Beyond explores brain function at different stages of life and how to maximize its efficiency with nutritional intervention. This book focuses on emerging health issues, including Alzheimer’s, Parkinson’s, Autism, ADHD in children and other brain disorders where supplement intervention is effective. In addition, sections address "herb-nutra psychiatry," a field of research focused on developing a comprehensive, cohesive evidence base to shift conceptual thinking surrounding the role of diet and nutrition in mental health. Intended for nutrition researchers, nutritionists, dieticians, regulatory bodies, health professionals, and students studying related fields, this useful reference links nutrition and brain health.

  • Provides coverage of nutritional psychiatry
  • Addresses cognitive health at all stages of the lifespan
  • Contains extensive coverage on vitamins, minerals, botanicals and other nutrients
  • Offers novel insight into cognitive dysfunctions, including depression and other neurodegenerative disorders
  • Explores the role of genomics and epigenetics, including coverage of the gut-brain axis
Contributors xi
1 Introduction
1(2)
Dilip Ghosh
References
2(1)
2 Role of food or food component in brain health
3(12)
Dilip Ghosh
Introduction
3(1)
Energy status and brain health
4(1)
Neuroactive in foods
4(2)
Omega-3 and phytochemicals: potential future therapeutic candidates
6(2)
Cognition beyond foods: just diet or lifestyle pattern?
8(1)
Food "liking" versus food "wanting"
8(1)
Diet, aging, and neurodegenerative diseases
8(1)
Diet, cognition, and epigenetics
9(1)
Microbiota-targeted functional foods for brain health
9(2)
Thinking outside the brain
11(1)
Conclusion
11(1)
References
11(4)
3 Bacopa monnieri for cognitive health--a review of molecular mechanisms of action
15(16)
Divya Purusothaman
Nehru Sai Suresh Chalichem
Bharathi Bethapudi
Sasikumar Murugan
Deepak Mundkinajeddu
Cognition
15(3)
Approved drugs as cognition enhancers
18(1)
Nutraceuticals for cognitive performance
18(1)
Bacopa monnieri for cognitive performance
19(1)
Neuronal molecular mechanisms of cognitive benefits of BM in relation to signal transduction
19(5)
Summary
24(1)
References
24(7)
4 Indian medicinal plants as drug leads in neurodegenerative disorders
31(16)
Rohit Sharma
Neha Garg
Deepanshu Verma
Preeti Rathi
Vineet Sharma
Kamil Kuca
Pradeep Kumar Prajapati
Abbreviations
31(1)
Introduction
31(1)
Methodology
32(1)
Etiopathology of neurodegenerative disorders
32(1)
Ayurvedic herbs: traditional usages in brain disorders
32(1)
Role of Indian ayurvedic herbs in neurodegenerative brain disorders
32(10)
Conclusion
42(2)
Acknowledgments
44(1)
References
44(3)
5 Role of nutraceuticals in the management of severe traumatic brain injury
47(10)
Ramesh Teegala
Introduction
47(1)
Traumatic brain injury
47(3)
Nutritional management in TBI
50(2)
Herbs and traditional medicines
52(1)
Conclusions
52(1)
References
53(4)
6 Understanding the relationship between oxidative stress and cognition in the elderly: targets for nutraceutical interventions
57(24)
Naomi Perry
Laura Martin
Frank Rosenfeldt
Ruchong Ou
Renee Rowsell
Con Stough
The aging population
57(1)
What is cognitive aging?
58(1)
What are the biological factors influencing cognitive aging?
58(1)
Oxidative stress
59(2)
Oxidative stress and cognition
61(2)
Potential nutraceutical targets for improving cognition via reducing oxidative stress
63(1)
Coenzyme Q10
63(1)
Pycnogenol
64(2)
Vitamins E and C
66(1)
Carotenoids
67(3)
Polyphenols
70(4)
Conclusions
74(1)
References
74(7)
7 Brain and mental health in Ayurveda
81(32)
Chandra Kant Katiyar
Satyajyoti Kanjilal
Avinash Narwaria
Ayurvedic principles of brain health
81(3)
Brain diseases in Ayurveda - Manas roga
84(2)
Ayurvedic drugs used in management of brain disorders
86(1)
Ayurvedic herbs in brain health - medhya rasayan herbs
86(24)
Acknowledgments
110(1)
References
110(3)
8 10 Persian herbal medicines used for brain health
113(12)
Zahra Ayati
Seyed Ahmad Emami
Gilles J. Guillemin
Diana Karamacoska
Dennis Chang
Introduction
113(1)
Herbal medicines for brain health
113(7)
Polyherbal formulations and synergistic effects
120(1)
Conclusion
120(1)
References
120(5)
9 Beneficial effects of nutraceuticals in healthy brain aging
125(16)
Preeticia Dkhar
Ramesh Sharma
Introduction
125(1)
Brain aging and associated neurodegenerative diseases
126(8)
Conclusion
134(1)
Acknowledgments
134(1)
References
134(7)
10 Investigating the acute effect of pomegranate extract on indicators of cognitive function in human volunteers: a double-blind placebo-controlled crossover trial
141(14)
Angela V.E. Stockton
Andrea Zangara
Emad A.S. Al-Dujaili
List of abbreviations
141(1)
Introduction
141(10)
Potential mechanisms
151(1)
Conclusions
151(1)
References
151(3)
Further reading
154(1)
11 Glucosinolates: paradoxically beneficial in fighting both brain cell death and cancer
155(14)
Zeenat Ladak
Mostafa Khairy
Edward A. Armstrong
Jerome Y. Yager
Introduction
155(1)
Background and significance
156(7)
Signaling apoptosis through the extrinsic pathway
163(1)
Redox signaling
163(1)
Effect on HDAC enzymes
163(1)
ERK pathway
164(1)
Activation of tumor suppressor genes: p53, p21, p27, and p73
164(1)
Endoplasmic reticulum (ER) stress
164(1)
The effect on cancer stem cells
164(1)
The effect on SMYD3 genes
164(1)
NrF2-ARE signaling pathway
165(1)
AMPK and SFA toxicity and protection
165(1)
Conclusion
165(1)
Acknowledgments
165(1)
References
165(4)
12 Efficacy of dietary polyphenols for neuroprotective effects and cognitive improvements
169(6)
Divya Chandradhara
Augustine Amalraj
Sreeraj Gopi
Introduction
169(1)
Neuroprotective effects of curcumin
170(1)
Neuroprotective effects of resveratrol
170(1)
Neuroprotective effects of EGCC isolated from green tea
171(1)
Application of other polyphenolic compounds in human central nervous system functions
171(1)
Conclusion
172(1)
References
172(3)
13 The gut microbiota--brain axis and role of probiotics
175(18)
Ruby Sound
Introduction
175(1)
Gut microbiota
176(1)
Gut microbiome and the gut-brain axis
176(1)
Impact of gut microbiota on CNS
177(1)
Gut microbiota--brain communication
178(2)
How does gut microbiota affect the brain?
180(1)
Microbiota-gut-brain axis and depression
181(1)
Microbiota-gut-brain axis and autism
181(3)
Prebiotics and probiotics
184(3)
Conclusion
187(1)
References
187(6)
14 The gut microbiome: its role in brain health
193(20)
Christine A. Houghton
Introduction
193(1)
The human gut microbiome--a new frontier in medicine
194(2)
The Gl tract and its microbiome as an ecosystem
196(1)
Shifting the therapeutic emphasis from the probiotic toward the host
197(5)
How intestinal microbes communicate with the host
202(2)
Other biochemical influences on neural function in the gut-brain axis
204(1)
Nutrition-specific requirements of the host and its microbiota
205(1)
How does nature maintain the gut-microbiome-brain axis?
206(1)
Therapeutic interventions
207(1)
Conclusion
207(1)
References
208(5)
15 The psychopharmacology of saffron, a plant with putative antidepressant and neuroprotective properties
213(14)
Dezso Csupor
Barbara Ioth
Javad Mottaghipisheh
Andrea Zangara
Emad A.S. Al-Dujaili
Introduction
213(1)
Traditional and ethnomedicinal uses
213(1)
Chemical constituents
214(1)
Stigma
214(1)
Flowers except stigma
214(1)
Tepal
215(1)
Stamen
215(1)
Mode of action
216(1)
Clinical applications
217(5)
Conclusions
222(1)
References
222(5)
16 Comprehensive review of Alzheimer's disease drugs (conventional, newer, and plant-derived) with focus on Bacopa monnieri
227(22)
Kaustubh S. Chaudhari
Introduction
227(1)
Alzheimer's disease
228(4)
Nutraceuticals in AD
232(1)
Bacopa monnieri
233(7)
Fundamental and clinical research in B. Monnieri in AD
240(3)
Bacopa monnieri clinical practice
243(2)
Conclusions
245(1)
References
246(3)
17 Nutraceuticals in neurodegenerative diseases
249(22)
Sharmistha Banerjee
Sayanta Dutta
Sumit Ghosh
Parames C. Sil
Introduction
249(2)
Alzheimer disease
251(3)
Huntington disease
254(2)
Parkinson disease
256(3)
Amyotrophic lateral sclerosis
259(2)
Conclusion
261(1)
References
262(9)
18 Transforming curry extract-spice to liposome-based curcumin: lipocurc to restore and boost brain health in COVID-19 syndrome
271(10)
Simon S. Chiu
Kristen Terpstra
Michel Woodbury-Farina
Vladimir Badmaev
Josh Varghese
Hana Raheb
Ed Lui
Zack Cernovsky
Yves Bureau
Mariwan Husni
John Copen
Mujeeb Shad
Autumn Carriere
Zahra Khazaeipool
Weam Sieffien
Marina Henein
Brendan Casola
Siddhansh Shrivastava
COVID-19 pandemic
271(1)
Curcumin pharmacology and COVID-19
272(2)
Nanotechnology, epigenetics, and PK studies of liposome-curcumin
274(2)
COVID-19 brain rehabilitation: role of epigenetics diet and exercise
276(2)
Summary
278(1)
References
278(3)
19 Cognitive health and nutrition: a millennial correlation
281(12)
Arun Balakrishnan
Muralidhara Padigaru
Abhijeet Morde
Molecular signaling of energy metabolism and synaptic plasticity
281(1)
Oxidative damage and cognition
282(1)
Nutrition and neurotransmitters
283(1)
Nutrition and brain well-being
283(2)
Correlation between metabolic diseases and psychiatric conditions
285(1)
Diet and cognitive health
286(1)
Cognitive enhancers
287(1)
Active sports and cognitive performance: role of nutritional supplements
287(1)
Diet and epigenetics
288(1)
Nutraceuticals as key drivers for brain health
288(1)
Future recommendations
288(1)
References
288(5)
20 Mediterranean diet and its components: potential to optimize cognition across the lifespan
293(14)
Sarah Gauci
Lauren M. Young
Helen Macpherson
David J. White
Sarah Benson
Andrew Pipingas
Andrew Scholey
Diet, cognition, and dementia
293(1)
Assessment of Mediterranean diet
293(1)
Mediterranean diet and cognition across the lifespan
294(6)
Mechanisms and food components
300(1)
Olive oil
301(1)
Fish
301(1)
Nuts
301(1)
Fruits and vegetables
302(1)
Practical translation into Western countries
302(1)
References
303(4)
21 Centella asiatica (Gotu kola) leaves: potential in neuropsychiatric conditions
307(22)
Prasad Arvind Thakurdesai
Introduction
307(1)
Psychological disorders
308(3)
Cognitive disorders
311(3)
Neurological disorders
314(4)
Neurodegenerative and neuroinflammatory disorders
318(2)
Recent advance: nasal delivery of CA extract
320(1)
References
320(9)
22 Big data for clinical trials
329(6)
Nikhil Verma
Introduction
329(1)
Role of big data in research
329(1)
Technology of big data
330(1)
Life cycle and management of data using technologies
331(1)
Approach of regulatory agencies
331(1)
Big healthcare data: security and privacy
332(1)
Big data = big prospects
332(1)
References
333(2)
23 The multifactorial contributions of Pycnogenol® for cognitive function improvement
335(8)
Frank Schoenlau
Introduction
335(1)
Pycnogenol® as a herbal medication
336(1)
Deteriorating cognitive function in the aging brain
336(1)
Mechanism of action of Pycnogenol®
337(1)
Pycnogenol® as a cognitive enhancer
337(2)
References
339(4)
24 Advancements in delivery of herbal drugs for cognitive disorders
343(14)
Nidhi Prakash Sapkal
Anwar Siraj Daud
Introduction
343(1)
Herbal drugs in neurological health
344(1)
Factors limiting brain delivery of herbal products
344(4)
Advancements in the brain delivery technologies
348(3)
Industrial applicability of these novel technologies and commercial viability
351(1)
Regulatory challenges
351(1)
Conclusion
352(1)
References
352(5)
25 Impact of cardiometabolic disease on cognitive function
357(12)
Bradley J. McEwen
Introduction
357(1)
Cardiometabolic disease
358(1)
The impact of cardiometabolic disease on brain and cognitive health
358(3)
The effect of nutritional medicine on cardiometabolic disease and cognitive function
361(3)
Conclusion
364(1)
References
365(4)
26 Vitamin B6, B9, and B-12: can these vitamins improve memory in Alzheimer's disease?
369(10)
Rohit Ghosh
Vitamin B6, B12, and folate
369(1)
Cognitive decline, dementia, and the homocysteine hypothesis--what is the evidence showing?
370(3)
Alzheimer's disease and the effect of vitamin B6, folate, and B12
373(1)
Clinical recommendations and application
374(1)
Conclusions
374(2)
References
376(3)
27 Sri Lankan medicinal herbs used for the management of neurodegenerative diseases of the brain
379(12)
W.A.L. Chandrasiri Waliwita
Introduction
379(1)
Neurodegenerative diseases of the brain
379(3)
Herbal medicines that could be recommended for the Neurodegenerative diseases of the brain
382(1)
Review on medicinal herbs used for the management of neurodegenerative diseases of the brain
383(4)
References
387(4)
28 Management of Alzheimer's Disease with nutraceuticals
391(18)
Jay Kant Yadav
Introduction
391(1)
Alzheimer's disease: the leading cause of dementia
392(1)
Understanding the origin of AD
393(3)
Social and economic impact
396(1)
Management and care of patients suffering with AD
396(1)
Treatment and care
396(1)
Nutraceuticals: an emerging trend in disease management
397(1)
Dietary components of nutraceuticals
397(4)
Conclusions
401(1)
References
401(8)
29 Nutraceuticals in brain health
409(32)
Swati Haldar
Souvik Ghosh
Viney Kumar
Saakshi Saini
Debrupa Lahiri
Partha Roy
Introduction to nutraceuticals
409(4)
Nutraceutical and overall brain health: Traditional versus modern outlook
413(9)
Mechanistic insights into nutraceuticals functioning as protectors of brain health
422(5)
Nutraceuticals from an evolutionary perspective
427(3)
Conclusion
430(1)
References
430(11)
30 Ayurveda and Brain health
441(14)
Bhushan Patwardhan
Hema Sharma Datta
Introduction - The brain and the nervous system
441(1)
Ayurvedic perspective of the nervous system--Majja dhatu and Majjavaha srotas
442(1)
Brain patterns and Dosha type
443(1)
Brain aging--Modern and Ayurvedic perspective
444(7)
Discussion and way forward
451(1)
References
452(3)
Index 455
Dr. Ghosh is a director at Nutriconnect, Sydney, Australia; Coordinator, Regulatory & projects, SOHO-Flordis International, Australia; Honorary Ambassador , Global Harmonization Initiative (GHI). With more than 20 years of experience in both pharmaceutical and food-nutrition industries, he is one of the pioneer researchers in the evaluation of the health claims opportunities of potential functional food ingredients & complementary medicines through an evaluation of the current scientific evidence base and related claims, and provides commentary on gaps in science including potential requirements for research such as human studies. Dr. Ghosh previously held positions in Organon (India) Ltd., a division of Organon International, BV and AKZO-NOBEL, The Netherlands; HortResearch, New Zealand; USDA-ARS, HNRCA at Tufts University, Boston; The Smart Foods Centre, University of Wollongong, Australia; and Neptune Bio-Innovations Pty Ltd, Sydney.