Contributors |
|
xi | |
|
|
1 | (2) |
|
|
|
2 | (1) |
|
2 Role of food or food component in brain health |
|
|
3 | (12) |
|
|
|
3 | (1) |
|
Energy status and brain health |
|
|
4 | (1) |
|
|
4 | (2) |
|
Omega-3 and phytochemicals: potential future therapeutic candidates |
|
|
6 | (2) |
|
Cognition beyond foods: just diet or lifestyle pattern? |
|
|
8 | (1) |
|
Food "liking" versus food "wanting" |
|
|
8 | (1) |
|
Diet, aging, and neurodegenerative diseases |
|
|
8 | (1) |
|
Diet, cognition, and epigenetics |
|
|
9 | (1) |
|
Microbiota-targeted functional foods for brain health |
|
|
9 | (2) |
|
Thinking outside the brain |
|
|
11 | (1) |
|
|
11 | (1) |
|
|
11 | (4) |
|
3 Bacopa monnieri for cognitive health--a review of molecular mechanisms of action |
|
|
15 | (16) |
|
|
Nehru Sai Suresh Chalichem |
|
|
|
|
|
|
15 | (3) |
|
Approved drugs as cognition enhancers |
|
|
18 | (1) |
|
Nutraceuticals for cognitive performance |
|
|
18 | (1) |
|
Bacopa monnieri for cognitive performance |
|
|
19 | (1) |
|
Neuronal molecular mechanisms of cognitive benefits of BM in relation to signal transduction |
|
|
19 | (5) |
|
|
24 | (1) |
|
|
24 | (7) |
|
4 Indian medicinal plants as drug leads in neurodegenerative disorders |
|
|
31 | (16) |
|
|
|
|
|
|
|
|
|
31 | (1) |
|
|
31 | (1) |
|
|
32 | (1) |
|
Etiopathology of neurodegenerative disorders |
|
|
32 | (1) |
|
Ayurvedic herbs: traditional usages in brain disorders |
|
|
32 | (1) |
|
Role of Indian ayurvedic herbs in neurodegenerative brain disorders |
|
|
32 | (10) |
|
|
42 | (2) |
|
|
44 | (1) |
|
|
44 | (3) |
|
5 Role of nutraceuticals in the management of severe traumatic brain injury |
|
|
47 | (10) |
|
|
|
47 | (1) |
|
|
47 | (3) |
|
Nutritional management in TBI |
|
|
50 | (2) |
|
Herbs and traditional medicines |
|
|
52 | (1) |
|
|
52 | (1) |
|
|
53 | (4) |
|
6 Understanding the relationship between oxidative stress and cognition in the elderly: targets for nutraceutical interventions |
|
|
57 | (24) |
|
|
|
|
|
|
|
|
57 | (1) |
|
|
58 | (1) |
|
What are the biological factors influencing cognitive aging? |
|
|
58 | (1) |
|
|
59 | (2) |
|
Oxidative stress and cognition |
|
|
61 | (2) |
|
Potential nutraceutical targets for improving cognition via reducing oxidative stress |
|
|
63 | (1) |
|
|
63 | (1) |
|
|
64 | (2) |
|
|
66 | (1) |
|
|
67 | (3) |
|
|
70 | (4) |
|
|
74 | (1) |
|
|
74 | (7) |
|
7 Brain and mental health in Ayurveda |
|
|
81 | (32) |
|
|
|
|
Ayurvedic principles of brain health |
|
|
81 | (3) |
|
Brain diseases in Ayurveda - Manas roga |
|
|
84 | (2) |
|
Ayurvedic drugs used in management of brain disorders |
|
|
86 | (1) |
|
Ayurvedic herbs in brain health - medhya rasayan herbs |
|
|
86 | (24) |
|
|
110 | (1) |
|
|
110 | (3) |
|
8 10 Persian herbal medicines used for brain health |
|
|
113 | (12) |
|
|
|
|
|
|
|
113 | (1) |
|
Herbal medicines for brain health |
|
|
113 | (7) |
|
Polyherbal formulations and synergistic effects |
|
|
120 | (1) |
|
|
120 | (1) |
|
|
120 | (5) |
|
9 Beneficial effects of nutraceuticals in healthy brain aging |
|
|
125 | (16) |
|
|
|
|
125 | (1) |
|
Brain aging and associated neurodegenerative diseases |
|
|
126 | (8) |
|
|
134 | (1) |
|
|
134 | (1) |
|
|
134 | (7) |
|
10 Investigating the acute effect of pomegranate extract on indicators of cognitive function in human volunteers: a double-blind placebo-controlled crossover trial |
|
|
141 | (14) |
|
|
|
|
|
141 | (1) |
|
|
141 | (10) |
|
|
151 | (1) |
|
|
151 | (1) |
|
|
151 | (3) |
|
|
154 | (1) |
|
11 Glucosinolates: paradoxically beneficial in fighting both brain cell death and cancer |
|
|
155 | (14) |
|
|
|
|
|
|
155 | (1) |
|
Background and significance |
|
|
156 | (7) |
|
Signaling apoptosis through the extrinsic pathway |
|
|
163 | (1) |
|
|
163 | (1) |
|
|
163 | (1) |
|
|
164 | (1) |
|
Activation of tumor suppressor genes: p53, p21, p27, and p73 |
|
|
164 | (1) |
|
Endoplasmic reticulum (ER) stress |
|
|
164 | (1) |
|
The effect on cancer stem cells |
|
|
164 | (1) |
|
The effect on SMYD3 genes |
|
|
164 | (1) |
|
NrF2-ARE signaling pathway |
|
|
165 | (1) |
|
AMPK and SFA toxicity and protection |
|
|
165 | (1) |
|
|
165 | (1) |
|
|
165 | (1) |
|
|
165 | (4) |
|
12 Efficacy of dietary polyphenols for neuroprotective effects and cognitive improvements |
|
|
169 | (6) |
|
|
|
|
|
169 | (1) |
|
Neuroprotective effects of curcumin |
|
|
170 | (1) |
|
Neuroprotective effects of resveratrol |
|
|
170 | (1) |
|
Neuroprotective effects of EGCC isolated from green tea |
|
|
171 | (1) |
|
Application of other polyphenolic compounds in human central nervous system functions |
|
|
171 | (1) |
|
|
172 | (1) |
|
|
172 | (3) |
|
13 The gut microbiota--brain axis and role of probiotics |
|
|
175 | (18) |
|
|
|
175 | (1) |
|
|
176 | (1) |
|
Gut microbiome and the gut-brain axis |
|
|
176 | (1) |
|
Impact of gut microbiota on CNS |
|
|
177 | (1) |
|
Gut microbiota--brain communication |
|
|
178 | (2) |
|
How does gut microbiota affect the brain? |
|
|
180 | (1) |
|
Microbiota-gut-brain axis and depression |
|
|
181 | (1) |
|
Microbiota-gut-brain axis and autism |
|
|
181 | (3) |
|
Prebiotics and probiotics |
|
|
184 | (3) |
|
|
187 | (1) |
|
|
187 | (6) |
|
14 The gut microbiome: its role in brain health |
|
|
193 | (20) |
|
|
|
193 | (1) |
|
The human gut microbiome--a new frontier in medicine |
|
|
194 | (2) |
|
The Gl tract and its microbiome as an ecosystem |
|
|
196 | (1) |
|
Shifting the therapeutic emphasis from the probiotic toward the host |
|
|
197 | (5) |
|
How intestinal microbes communicate with the host |
|
|
202 | (2) |
|
Other biochemical influences on neural function in the gut-brain axis |
|
|
204 | (1) |
|
Nutrition-specific requirements of the host and its microbiota |
|
|
205 | (1) |
|
How does nature maintain the gut-microbiome-brain axis? |
|
|
206 | (1) |
|
Therapeutic interventions |
|
|
207 | (1) |
|
|
207 | (1) |
|
|
208 | (5) |
|
15 The psychopharmacology of saffron, a plant with putative antidepressant and neuroprotective properties |
|
|
213 | (14) |
|
|
|
|
|
|
|
213 | (1) |
|
Traditional and ethnomedicinal uses |
|
|
213 | (1) |
|
|
214 | (1) |
|
|
214 | (1) |
|
|
214 | (1) |
|
|
215 | (1) |
|
|
215 | (1) |
|
|
216 | (1) |
|
|
217 | (5) |
|
|
222 | (1) |
|
|
222 | (5) |
|
16 Comprehensive review of Alzheimer's disease drugs (conventional, newer, and plant-derived) with focus on Bacopa monnieri |
|
|
227 | (22) |
|
|
|
227 | (1) |
|
|
228 | (4) |
|
|
232 | (1) |
|
|
233 | (7) |
|
Fundamental and clinical research in B. Monnieri in AD |
|
|
240 | (3) |
|
Bacopa monnieri clinical practice |
|
|
243 | (2) |
|
|
245 | (1) |
|
|
246 | (3) |
|
17 Nutraceuticals in neurodegenerative diseases |
|
|
249 | (22) |
|
|
|
|
|
|
249 | (2) |
|
|
251 | (3) |
|
|
254 | (2) |
|
|
256 | (3) |
|
Amyotrophic lateral sclerosis |
|
|
259 | (2) |
|
|
261 | (1) |
|
|
262 | (9) |
|
18 Transforming curry extract-spice to liposome-based curcumin: lipocurc to restore and boost brain health in COVID-19 syndrome |
|
|
271 | (10) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
271 | (1) |
|
Curcumin pharmacology and COVID-19 |
|
|
272 | (2) |
|
Nanotechnology, epigenetics, and PK studies of liposome-curcumin |
|
|
274 | (2) |
|
COVID-19 brain rehabilitation: role of epigenetics diet and exercise |
|
|
276 | (2) |
|
|
278 | (1) |
|
|
278 | (3) |
|
19 Cognitive health and nutrition: a millennial correlation |
|
|
281 | (12) |
|
|
|
|
Molecular signaling of energy metabolism and synaptic plasticity |
|
|
281 | (1) |
|
Oxidative damage and cognition |
|
|
282 | (1) |
|
Nutrition and neurotransmitters |
|
|
283 | (1) |
|
Nutrition and brain well-being |
|
|
283 | (2) |
|
Correlation between metabolic diseases and psychiatric conditions |
|
|
285 | (1) |
|
Diet and cognitive health |
|
|
286 | (1) |
|
|
287 | (1) |
|
Active sports and cognitive performance: role of nutritional supplements |
|
|
287 | (1) |
|
|
288 | (1) |
|
Nutraceuticals as key drivers for brain health |
|
|
288 | (1) |
|
|
288 | (1) |
|
|
288 | (5) |
|
20 Mediterranean diet and its components: potential to optimize cognition across the lifespan |
|
|
293 | (14) |
|
|
|
|
|
|
|
|
Diet, cognition, and dementia |
|
|
293 | (1) |
|
Assessment of Mediterranean diet |
|
|
293 | (1) |
|
Mediterranean diet and cognition across the lifespan |
|
|
294 | (6) |
|
Mechanisms and food components |
|
|
300 | (1) |
|
|
301 | (1) |
|
|
301 | (1) |
|
|
301 | (1) |
|
|
302 | (1) |
|
Practical translation into Western countries |
|
|
302 | (1) |
|
|
303 | (4) |
|
21 Centella asiatica (Gotu kola) leaves: potential in neuropsychiatric conditions |
|
|
307 | (22) |
|
Prasad Arvind Thakurdesai |
|
|
|
307 | (1) |
|
|
308 | (3) |
|
|
311 | (3) |
|
|
314 | (4) |
|
Neurodegenerative and neuroinflammatory disorders |
|
|
318 | (2) |
|
Recent advance: nasal delivery of CA extract |
|
|
320 | (1) |
|
|
320 | (9) |
|
22 Big data for clinical trials |
|
|
329 | (6) |
|
|
|
329 | (1) |
|
Role of big data in research |
|
|
329 | (1) |
|
|
330 | (1) |
|
Life cycle and management of data using technologies |
|
|
331 | (1) |
|
Approach of regulatory agencies |
|
|
331 | (1) |
|
Big healthcare data: security and privacy |
|
|
332 | (1) |
|
|
332 | (1) |
|
|
333 | (2) |
|
23 The multifactorial contributions of Pycnogenol® for cognitive function improvement |
|
|
335 | (8) |
|
|
|
335 | (1) |
|
Pycnogenol® as a herbal medication |
|
|
336 | (1) |
|
Deteriorating cognitive function in the aging brain |
|
|
336 | (1) |
|
Mechanism of action of Pycnogenol® |
|
|
337 | (1) |
|
Pycnogenol® as a cognitive enhancer |
|
|
337 | (2) |
|
|
339 | (4) |
|
24 Advancements in delivery of herbal drugs for cognitive disorders |
|
|
343 | (14) |
|
|
|
|
343 | (1) |
|
Herbal drugs in neurological health |
|
|
344 | (1) |
|
Factors limiting brain delivery of herbal products |
|
|
344 | (4) |
|
Advancements in the brain delivery technologies |
|
|
348 | (3) |
|
Industrial applicability of these novel technologies and commercial viability |
|
|
351 | (1) |
|
|
351 | (1) |
|
|
352 | (1) |
|
|
352 | (5) |
|
25 Impact of cardiometabolic disease on cognitive function |
|
|
357 | (12) |
|
|
|
357 | (1) |
|
|
358 | (1) |
|
The impact of cardiometabolic disease on brain and cognitive health |
|
|
358 | (3) |
|
The effect of nutritional medicine on cardiometabolic disease and cognitive function |
|
|
361 | (3) |
|
|
364 | (1) |
|
|
365 | (4) |
|
26 Vitamin B6, B9, and B-12: can these vitamins improve memory in Alzheimer's disease? |
|
|
369 | (10) |
|
|
Vitamin B6, B12, and folate |
|
|
369 | (1) |
|
Cognitive decline, dementia, and the homocysteine hypothesis--what is the evidence showing? |
|
|
370 | (3) |
|
Alzheimer's disease and the effect of vitamin B6, folate, and B12 |
|
|
373 | (1) |
|
Clinical recommendations and application |
|
|
374 | (1) |
|
|
374 | (2) |
|
|
376 | (3) |
|
27 Sri Lankan medicinal herbs used for the management of neurodegenerative diseases of the brain |
|
|
379 | (12) |
|
W.A.L. Chandrasiri Waliwita |
|
|
|
379 | (1) |
|
Neurodegenerative diseases of the brain |
|
|
379 | (3) |
|
Herbal medicines that could be recommended for the Neurodegenerative diseases of the brain |
|
|
382 | (1) |
|
Review on medicinal herbs used for the management of neurodegenerative diseases of the brain |
|
|
383 | (4) |
|
|
387 | (4) |
|
28 Management of Alzheimer's Disease with nutraceuticals |
|
|
391 | (18) |
|
|
|
391 | (1) |
|
Alzheimer's disease: the leading cause of dementia |
|
|
392 | (1) |
|
Understanding the origin of AD |
|
|
393 | (3) |
|
Social and economic impact |
|
|
396 | (1) |
|
Management and care of patients suffering with AD |
|
|
396 | (1) |
|
|
396 | (1) |
|
Nutraceuticals: an emerging trend in disease management |
|
|
397 | (1) |
|
Dietary components of nutraceuticals |
|
|
397 | (4) |
|
|
401 | (1) |
|
|
401 | (8) |
|
29 Nutraceuticals in brain health |
|
|
409 | (32) |
|
|
|
|
|
|
|
Introduction to nutraceuticals |
|
|
409 | (4) |
|
Nutraceutical and overall brain health: Traditional versus modern outlook |
|
|
413 | (9) |
|
Mechanistic insights into nutraceuticals functioning as protectors of brain health |
|
|
422 | (5) |
|
Nutraceuticals from an evolutionary perspective |
|
|
427 | (3) |
|
|
430 | (1) |
|
|
430 | (11) |
|
30 Ayurveda and Brain health |
|
|
441 | (14) |
|
|
|
Introduction - The brain and the nervous system |
|
|
441 | (1) |
|
Ayurvedic perspective of the nervous system--Majja dhatu and Majjavaha srotas |
|
|
442 | (1) |
|
Brain patterns and Dosha type |
|
|
443 | (1) |
|
Brain aging--Modern and Ayurvedic perspective |
|
|
444 | (7) |
|
Discussion and way forward |
|
|
451 | (1) |
|
|
452 | (3) |
Index |
|
455 | |