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E-grāmata: Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases

  • Formāts: 576 pages
  • Izdošanas datums: 06-Oct-1997
  • Izdevniecība: CRC Press Inc
  • ISBN-13: 9781482292213
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  • Formāts: 576 pages
  • Izdošanas datums: 06-Oct-1997
  • Izdevniecība: CRC Press Inc
  • ISBN-13: 9781482292213

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As the public has become aware, "oxygen is a dangerous friend." As codiscoverer of the AIDS virus, Montagnier (Institut Pasteur; Paris, France) presents incisive discussions for those in the biomedical sciences by over 200 international authorities on the significance of oxidant/anti-oxidant balance and the cytotoxicity of free radicals in disease genesis, prevention, and treatment. Current hypotheses from epidemiological evidence favor the idea that lowering oxidative stress correlates with decreased risk, and of clinical benefit, in aging and conditions such as heart disease, cancers, cataracts, rheumatoid arthritis, and diabetes. In disorders such as AIDS and Alzheimers, oxidative stress appears to occur as a secondary complication. Annotation c. by Book News, Inc., Portland, Or.

Based on a conference on Oxidative Stress and Redox Regulation, held at the Pasteur Institute, Paris, this work examines fundamental, chemical, biological and medical studies of free radicals on different targets and the consequences of their reactivity. It covers the chemistry and biochemistry of free radicals, free radicals as second messengers that group the activation of transcription factors and enzymes, the importance of the antioxidant system in cell metabolism regulation, and the role of free radicals and antioxidants in disease management. The editors of this work are three of the most respected pioneers in the field. Dr. Montagnier is credited as the discoverer of HIV.
Series Introduction iii(4) Lester Packer Enrique Cadenas Preface vii Oxidative Stress in Cell Biology and Biochemistry 1(28)
1. The Importance of Oxidant-Antioxidant Balance 1(8) Joe M. McCord
2. The Effect of Oxidative Stress on Cells by Oxygen Radicals and Its Inhibition by Antioxidants 9(6) Mareyuki Takahashi Etsuo Niki
3. Cytotixicity of Radiation-Derived Reactive Oxygen Species 15(14) Manfred Saran Wolf Bors Oxidative Stress and Cellular Signaling 29(150)
4. Regulation of the Bacterial Response to Hydrogen Peroxide 29(6) Gisela Storz Ming Zheng Aixia Zhang Ines Kullik Michel Toledano Shoshy Altuvia
5. Activation of Lymphocyte Signal Pathways by Oxidative Stress: Role of Tyrosine Kinases and Phosphatases 35(10) Gary L. Schieven
6. Oxidant-mediated Modulation of Phospholipases in Endothelial Cells: Possible Implication in Vascular Disorders 45(18) V. Natarajan Suryanarayana Vepa William M. Scribner
7. NFkB Transcription Factor Activation: Importance of the Redox Regulation 63(12) Bernard Piret Giuseppina Bonizzi Marie-Paule Merville Vincent Bours Jacques Piette
8. Redox Regulation of the NFkB Signaling Pathway and Disease Control 75(8) Takashi Okamoto Shinsaku Sakurada Tetsuji Kato Akihiko Yoneyama Keiichi Tozawa Jian-Ping Yang Naoko Takahashi
9. Mechanism of Activation of NFkB by Hydrogen Peroxide 83(6) Kirsty G. McPherson John R. Babson Anthony J. Kettle Christine C. Winterbourn
10. Self-regulation of the NFkB/IkB Alpha System, and Its Positive and Negative Control by the Cellular Redox Status 89(8) Jean-Louis Virelizier Fernando Arenzana-Seisdedos Manuel Rodriguez Catherine Dargemont Ronald T. Hay Nicholas Hunt
11. The Role of Hydrogen Peroxide in Signal Transduction and the Involvement of Iron 97(16) B.S. van Asbeck R.C. Sprong T. van der Bruggen J.F.L.M. van Oirschot J.C.C. Borleffs
12. Redox Regulation of Heat Shock Protein Expression and Protective Effects Against Oxidative Stress 113(14) Abdelhamid El Yaagoubi Ewa Mariethoz Muriel R. Jacquier-Sarlin Barbara S. Polla
13. Low-Density Lipoproteins Modulate Nitric Oxide and Heme Oxygenase Signal Transduction Pathways in Vascular Endothelium and Smooth Muscle 127(12) R.C.M. Siow M.T. Jay H. Sato J.D. Pearson G.E. Mann
14. Nitric Oxide-stimulated Tyrosine Phosphorylation-dependent Signaling Pathways in Cultured Cells 139(8) Hugo P. Monteiro Laura C.B. Oliveira Tereza M.S. Peranovich Renatta G. Penha Arnold Stern
15. Regulation of Cell Activation by Receptors for IgG 147(16) Marc Daeron Wolf H. Fridman
16. Signal Transduction Pathways Activated by Mitogenic Neuropeptides 163(16) Enrique Rozengurt Oxidative Stress and Apoptosis 179(44)
17. Glutathione Metabolism During Apoptosis 179(12) Diels J. van den Dobbelsteen C. Stefan I. Noble Astrid Samuelsson Sten Orrenius Andrew F.G. Slater
18. Endogenously Generated Superoxide and Hydrogen Peroxide in the Redox Modulation of Cell Proliferation, Apoptosis, and Virus Replication 191(8) Roy H. Burdon
19. Deoxy-D-Ribose-Induced GSH Depletion and Induction of Apoptosis in Human Quiescent Peripheral Blood Mononuclear Cells: Effects of N-Acetyl Cysteine and L-Buthionine-(S,R)-sulfoximine 199(6) B. Botti D. Monti S. Macchioni S. Bergamini F. Tropea A. Tomasi V. Vannini C. Franceschi
20. Nitric Oxide and Hydrogen Peroxide Production during Apoptosis of Human Neutrophils 205(8) Juanita Bustamante Cecilia Carreras Natalia Riobo Alexis Tovar Gonzalo Montero Juan Jose Poderoso Alberto Boveris
21. The Mitochondrion as a Sensor/Effector of Oxidative Stress During Apoptosis 213(10) Philippe Marchetti Santos A. Susin Naoufal Zamzami Guido Kroemer Oxidative Stress and Antioxidants 223(128)
22. Antioxidants and the Regulation of Reactive Iron 223(6) John M.C. Gutteridge
23. Redox Regulation by the Thioredoxin and Glutaredoxin Systems 229(18) Arne Holmgren Elias S.J. Arner Fredrik Aslund Mikael Bjornstedt Zhong Liangwei Johanna Ljung Hajime Nakamura Dragana Nikitovic
24. Thioredoxin/Adult T Cell Leukemia-Derived Factor as the Key Redox Regulator of Signaling 247(4) Junji Yodoi Yoshihisa Taniguchi Tetsuro Sasada Kiichi Hirota
25. Therapeutic Potential of the Antioxidant and Redox Properties of XXX-Lipoic Acid 251(18) Chandan K. Sen Sashwati Roy Lester Packer
26. Glutathione Compartmentation and Oxidative Stress 269(16) Melani K. Savage Donald J. Reed
27. Flavonoid Functions In Vivo: Are They Predominantly Antioxidant? 285(20) Wolf Bors
28. Immunoregulatory Properties of Superoxide Dismutase 305(8) E. Postaire B. Dugas P. Debre C. Gudin
29. Pharmacological Inhibition of Endothelial Cytoskeleton Alterations Induced by Hydrogen Peroxide and TNF-XXX 313(10) P. dAlessio M. Moutet C. Marsac I.J. Chaudiere
30. Perinatal Development of Superoxide Dismutase and Other Antioxidant Enzyme Activities in Rat-brain Mitochondria 323(10) Ingrid Wiswedel Sigrid Hoffmann Heiko Noack Wolfgang Augustin
31. Coexistence of a Reactive Oxygen Cycle with Q Cycle and H(+)-Cycle in the Respiratory Chain: A Hypothesis for the Generation, Partitioning, Targeting, and Functioning of Superoxide in Mitochondria 333(18) Shu-sen Liu Oxidative Stress and Cancer 351(22)
32. Endogenous Oxidative DNA Damage and Spontaneous Mutagenesis: Role of 8-Oxoguanine 351(8) Serge Boiteux
33. The Elevated Serum Level of Thioredoxin in Patients with Malignant Disease and Chronic Inflammatory Diseases 359(10) Hiro Wakasugi Kunihisa Miyazaki Michio Miyata Masaaki Terada
34. The Role of Free Radicals in Antitumor Effects of Various Cancer Treatments 369(4) Toshikazu Yoshikawa Satoshi Kokura Motoharu Kondo Oxidative Stress and AIDS 373(96)
35. The Role of Cysteine and Glutathione in the Pathogenesis of HIV Infection: Effects of Treatment with N-Acetylcysteine 373(6) Wulf Droge Hans-Peter Eck Heike Schenk Klaus Schulze-Osthoff Dagmar Galter George Shubinsky Sabine Mihm Volker Hack Ralf Kinscherf
36. Low Glutathione Levels in CD4 T Cells Predict Poor Survival in AIDS; N-Acetylcysteine May Improve Survival 379(10) Leonard A. Herzenberg Stephen C. De Rosa Leonore A. Herzenberg
37. Modulation of HIV-1 Long Terminal Repeat by Arachidonic Acid 389(10) Simonetta Camandola Tiziana Musso Gabriella Leonarduzzi Rita Carini Luigi Varesio Patrick A. Baeuerle Giuseppe Poli
38. Protein Degradation in Lymphocytes as an Indicator of Oxidative Stress in HIV Infection 399(10) Giuseppe Piedimonte Mauro Magnani Dario Corsi Javier F. Torres Roca Denise Guetard Luc Montagnier
39. Oxidative Stress and AIDS: One-year Supplementation of HIV-positive Patients with Selenium or beta-Carotene 409(20) C. Sergeant C. Hamon M. Simonoff J. Constans E. Peuchant M.C. Delmas J.L. Pellegrin I. Pellegrin M. Clerc B. Leng H. Fleury C. Conri
40. Glutathione Oxidation and Mitochondrial DNA Damage in AIDS: Effect of Zidovudine 429(8) Jose Vina Jose Garcia-de-la-Asuncion Maria L. Del Olmo Arantxa Millan Juan Sastre Jose A. Martin Federico V. Pallardo
41. Effect of L-Carnitine Treatment In Vivo on Apoptosis and Ceramide Generation by Peripheral Blood Lymphocytes from AIDS Patients 437(10) M.G. Cifone E. Alesse L. Di Marzio P. Roncaioli F. Zazzeroni S. Moretti G. Famularo S. Marcellini G. Santini V. Trinchieri E. Nucera C. De Simone
42. Nutriceutical Modulation of Glutathione with a Humanized Native Milk Serum Protein Isolate, IMMUNOCAL(TM): Application in AIDS and Cancer 447(16) Sylvain Baruchel Ginette Viau Rene Olivier Gustavo Bounos Mark A. Wainberg
43. Successful Antioxidant Therapy Including Superoxide Dismutase Associated with Antiretroviral Therapy in an HIV-Infected Patient with Hepatitis B-related Cirrhosis 463(6) J. Emerit E. Postaire D. Bonnefont-Rousselot O. Lopez F. Bricaire Oxidative Stress in Neurodegenerative Diseases and Other Pathologies 469(78)
44. Parkinsons Disease, Apoptosis, and Oxidative Stress 469(16) Merle Ruberg Valentine France-Lanord Bernard Brugg Stephane Hunot Philippe Anglade Philippe Damier Baptiste Faucheux Yves Agid
45. Protein Oxidation and Glycation in Neurodegenerative Diseases 485(12) Mark A. Smith George Perry Lawrence M. Sayre
46. Glycation as Oxidative Stress and Redox Regulation: Implications for Aging, Diabetes, and Familial Amyotrophic Lateral Sclerosis 497(6) Naoyuki Taniguchi Junichi Fujii Hideaki Kaneto Michio Asahi Theingi Myint Nobuko Miyazawa Keiichiro Suzuki Kazi Nazrul Islam
47. Oxidative Stress in Ischemia-Reperfusion: Reillys Irritation Syndrome Revisited 503(4) Makoto Suematsu Masaharu Tsuchiya
48. Evaluation of the Antiperoxidase Defense System of the Lens Utilizing GSH Peroxidase Transgenics and Knockouts 507(10) Abraham Spector Ye-Shih Ho Ren-Rong Wang Wanchao Ma Yinqing Yang Wan-Cheng Li
49. The Rheumatoid Joint: Redox-Paradox? 517(20) Vanessa Gilston David R. Blake Paul G. Winyard
50. Chronic Oxidative Stress in Rheumatoid Arthritis: Implications for T Cell Function 537(10) Madelon M. Maurice Hajime Nakamura Ellen A.M. van der Voort Sussanne Thorell Anita I. van Vliet Paul-Peter Tak Ferdinand C. Breedveld Cornelis L. Verweij Index 547
Montagnier, Luc; Olivier, Rene; Pasquier, Catherine