Preface to the sixth edition |
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xv | |
Acknowledgments |
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xvii | |
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1 An overview of chemical bioregulation in vertebrates |
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1 | (20) |
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I The comparative vertebrate approach |
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1 | (3) |
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II The origins of bioregulation |
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4 | (1) |
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III Categories of bioregulators |
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4 | (4) |
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IV General organization of bioregulatory systems |
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8 | (1) |
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V Cell and tissue organization of bioregulatory systems |
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9 | (4) |
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13 | (6) |
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VII Organization and goals for this textbook |
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19 | (1) |
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19 | (1) |
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20 | (1) |
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2 Methods to study bioregulation |
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21 | (22) |
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21 | (5) |
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II Methods of endocrine analysis |
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26 | (6) |
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III Molecular biology and bioregulation |
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32 | (6) |
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38 | (1) |
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39 | (1) |
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40 | (1) |
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40 | (3) |
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3 Synthesis, metabolism, and actions of bioregulators |
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43 | (48) |
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I Amino acids, amines, peptides, and proteins |
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43 | (21) |
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64 | (17) |
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81 | (5) |
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86 | (2) |
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88 | (1) |
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88 | (1) |
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89 | (2) |
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4 Organization of the mammalian hypothalamus-pituitary axes |
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91 | (60) |
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I The mammalian pituitary |
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94 | (7) |
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II The mammalian hypothalamus |
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101 | (7) |
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III Tropic hormones of the adenohypophysis |
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108 | (12) |
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IV Regulation of tropic hormone secretion in mammals |
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120 | (13) |
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V The nonapeptide hormones |
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133 | (4) |
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137 | (7) |
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VII Clinical aspects of the neuroendocrine system |
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144 | (2) |
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146 | (1) |
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147 | (1) |
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148 | (3) |
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5 The hypothalamus-pituitary system in nonmammalian vertebrates |
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151 | (54) |
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I The hypothalamus of nonmammalian vertebrates |
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152 | (4) |
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II The pituitary gland of fishes: anatomical and cytological considerations |
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156 | (8) |
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III The pituitary of tetrapod vertebrates: anatomical and cytological considerations |
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164 | (1) |
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IV Tropic hormones of nonmammalian vertebrates |
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165 | (15) |
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V Comparative aspects of hypothalamic control of pituitary function in nonmammals |
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180 | (11) |
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VI Nonapeptide neurohormones of the nonmammalian pars nervosa |
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191 | (3) |
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VII The epiphysial complex of nonmammals |
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194 | (7) |
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201 | (1) |
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Study questions and study activities |
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202 | (1) |
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202 | (3) |
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6 The hypothalamus-pituitary-thyroid (HPT) axis of mammals |
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205 | (26) |
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I Some historical aspects of thyroid physiology |
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205 | (2) |
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II Development and organization of the mammalian thyroid gland |
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207 | (1) |
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III Synthesis, secretion, action, and metabolism of thyroid hormones |
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207 | (10) |
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IV Factors that influence thyroid function in mammals |
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217 | (2) |
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V Biological actions of thyroid hormones in mammals |
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219 | (3) |
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VI Clinical aspects of thyroid function |
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222 | (5) |
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227 | (1) |
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228 | (1) |
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229 | (2) |
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7 The hypothalamus-pituitary-thyroid (HPT) axis of nonmammalian vertebrates |
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231 | (28) |
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I Evolution of the thyroid gland and its functions |
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231 | (7) |
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II Methods for studying comparative thyroid function |
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238 | (1) |
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III Comparative vertebrate thyroid physiology |
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238 | (17) |
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IV Thyroid hormone interactions with other hormones |
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255 | (1) |
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255 | (1) |
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256 | (1) |
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256 | (3) |
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8 The mammalian adrenal glands: cortical and chromaffin cells |
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259 | (32) |
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I The mammalian adrenal cortex |
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260 | (3) |
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II Biosynthesis (corticosteroidogenesis), release, transport, and metabolism of corticosteroids |
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263 | (2) |
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III Actions of glucocorticoids |
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265 | (6) |
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IV Allostasis and allostatic load |
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271 | (1) |
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V Aldosterone: the principal mammalian "mineralocorticoid" |
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272 | (6) |
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VI Clinical aspects of the adrenal axis |
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278 | (5) |
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VII The mammalian adrenal medulla |
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283 | (4) |
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287 | (1) |
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287 | (1) |
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288 | (3) |
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9 Comparative aspects of vertebrate adrenals |
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291 | (24) |
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I Comparative aspects of adrenocortical tissue |
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291 | (8) |
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II Corticosteroid receptors |
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299 | (1) |
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III Physiological roles for corticosteroids in nonmammalian vertebrates |
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299 | (7) |
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IV Renin-angiotensin system in nonmammals |
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306 | (3) |
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V Natriuretic peptides in nonmammalian vertebrates |
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309 | (1) |
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VI Evolution of chromaffin tissue and adrenal medullary hormones |
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310 | (1) |
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311 | (1) |
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311 | (1) |
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311 | (4) |
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10 The endocrinology of mammalian reproduction |
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315 | (56) |
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I General features of mammalian reproduction |
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316 | (8) |
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II Reproduction in eutherian mammals |
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324 | (5) |
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III Endocrine regulation of reproduction in eutherian males |
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329 | (6) |
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IV Endocrine regulation in eutherian females |
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335 | (17) |
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V Reproductive cycles in selected eutherian females |
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352 | (6) |
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VI Reproduction in monotremes and marsupials |
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358 | (4) |
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VII Major human endocrine disorders related to reproduction |
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362 | (3) |
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365 | (1) |
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366 | (1) |
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367 | (4) |
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11 Comparative aspects of vertebrate reproduction |
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371 | (66) |
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I Some general features of vertebrate reproduction |
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371 | (9) |
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II Reproduction in agnathan fishes: cyclostomes |
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380 | (2) |
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III Reproduction in chondrichthyean fishes |
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382 | (2) |
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IV Reproduction in bony fishes |
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384 | (11) |
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V Reproduction in amphibians |
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395 | (17) |
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VI Reproduction in reptiles |
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412 | (7) |
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VII Reproduction in birds |
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419 | (9) |
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428 | (2) |
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430 | (1) |
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430 | (7) |
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12 Chemical regulation of feeding, digestion, and metabolism |
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437 | (42) |
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437 | (9) |
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II Regulation of digestion |
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446 | (11) |
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III The mammalian pancreas |
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457 | (8) |
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IV Hormones regulating mammalian metabolism |
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465 | (5) |
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V Clinical aspects of metabolism |
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470 | (5) |
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475 | (1) |
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476 | (1) |
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477 | (2) |
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13 Comparative aspects of feeding, digestion, and metabolism |
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479 | (20) |
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I Hormones and regulation of feeding in nonmammals |
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479 | (3) |
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II Hormones and digestion in nonmammals |
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482 | (4) |
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III Comparative aspects of the endocrine pancreas |
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486 | (10) |
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496 | (1) |
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496 | (1) |
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497 | (2) |
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14 Regulation of calcium and phosphate homeostasis in vertebrates |
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499 | (28) |
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I Importance of calcium and phosphate |
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499 | (2) |
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II Bone formation and resorption in mammals |
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501 | (1) |
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III Endocrine regulation of calcium and phosphate homeostasis in mammals |
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502 | (11) |
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IV Major clinical disorders associated with calcium metabolism |
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513 | (2) |
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V Calcium-phosphate homeostasis in nonmammalian vertebrates |
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515 | (9) |
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524 | (2) |
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526 | (1) |
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526 | (1) |
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15 Environmental endocrinology of vertebrates |
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527 | (42) |
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I Natural environmental factors affecting vertebrate endocrine systems |
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527 | (9) |
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II Endocrine-disrupting chemicals (EDCs) |
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536 | (28) |
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564 | (1) |
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565 | (1) |
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565 | (4) |
Appendix A Abbreviations |
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569 | (10) |
Appendix B Vertebrate phylogeny and evolution |
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579 | (8) |
Appendix C Amino acid abbreviations |
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587 | (2) |
Appendix D Bioassays |
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589 | (8) |
Appendix E Units for measuring hormones |
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597 | (2) |
Appendix F Vertebrate tissue types |
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599 | (4) |
Appendix G Metabolic pathways |
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603 | (8) |
Index |
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611 | |