National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Sarah H. Beachy, Steve Olson, Siobhan Addie
Implementation research is designed to generate insights and knowledge about implementation processes, barriers, facilitators, and strategies, explained Brian Mittman, a research scientist at Kaiser Permanente Research. Workshop speakers examined...Lasīt vairāk
Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Adam C. Berger, Steve Olson, Sarah H. Beachy
The inclusion of genomic data in a knowledge-generating health care system infrastructure is one promising way to harness the full potential of that information to provide better patient care. In such a system, clinical practice and research influen...Lasīt vairāk
Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Steve Olson, Sarah H. Beachy, Samuel G. Johnson, Adam C. Berger
Many health care providers do not have either the knowledge or the tools they need in order to apply genetic information in their day-to-day practices. This lack of support is contributing to a substantial delay in the translation of genetic researc...Lasīt vairāk
Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Adam C. Berger, Steve Olson, Samuel G. Johnson, Sarah H. Beachy
Rapid advances in technology have lowered the cost of sequencing an individuals genome from the several billion dollars that it cost a decade ago to just a few thousand dollars today and have correspondingly greatly expanded the use of genomic info...Lasīt vairāk
Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Adam C. Berger, Steve Olson, Samuel G. Johnson, Sarah H. Beachy
Drug development can be time-consuming and expensive. Recent estimates suggest that, on average, it takes 10 years and at least 1 billion to bring a drug to market. Given the time and expense of developing drugs de novo, pharmaceutical companies ha...Lasīt vairāk
Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Steve Olson, Adam C. Berger, Sarah H. Beachy
Scientific advances such as the sequencing of the human genome have created great promise for improving human health by providing a greater understanding of disease biology and enabling the development of new drugs, diagnostics, and preventive servi...Lasīt vairāk
Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Adam C. Berger, Steve Olson, Samuel G. Johnson, Sarah H. Beachy
Many drug developers have examined new strategies for creating efficiencies in their development processes, including the adoption of genomics-based approaches. Genomic data can identify new drug targets for both common and rare diseases, can predic...Lasīt vairāk
Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Adam C. Berger, Steve Olson, Samuel G. Johnson, Sarah H. Beachy
The process for translating basic science discoveries into clinical applications has historically involved a linear and lengthy progression from initial discovery to preclinical testing, regulatory evaluation and approval, and, finally, use in clini...Lasīt vairāk
Center for Medical Technology Policy, Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Steve Olson, Adam C. Berger
Presents the summary of a workshop convened in May 2012 by the Roundtable on Translating Genomic-Based Research for Health and the Center for Medical Technology Policy of the Institute of Medicine to foster the identified need for further sustained...Lasīt vairāk
Forum on Drug Discovery, Development, and Translation, Forum on Neuroscience and Nervous System Disorders, National Cancer Policy Forum, Roundtable on Translating Genomic-Based Research on Health, Board on Health Sciences Poli
Forum on Drug Discovery, Development, and Translation, Forum on Neuroscience and Nervous System Disorders, National Cancer Policy Forum, Roundtable on Translating Genomic-Based Research on Health, Board on Health Sciences Poli
(Izdošanas datums: 07-May-2013, Hardback, Izdevniecība: National Academies Press, ISBN-13: 9780309384841)
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Pharmaceutical companies, academic researchers, and government agencies such as the Food and Drug Administration and the National Institutes of Health all possess large quantities of clinical research data. If these data were shared more widely...Lasīt vairāk
The number of new drug approvals has remained reasonably steady for the past 50 years at around 20 to 30 per year, while at the same time the total spending on health-related research and development has tripled since 1990. There are many suspected...Lasīt vairāk
The sequencing of the human genome and the identification of associations between specific genetic variants and diseases have led to an explosion of genomic-based diagnostic tests. These tests have the potential to direct therapeutic interventions,...Lasīt vairāk
Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine, Steve Olson, Sarah H. Beachy, Claire Giammaria, Adam C. Berger
The initial sequencing of the human genome, carried out by an international group of experts, took 13 years and 2.7 billion to complete. In the decade since that achievement, sequencing technology has evolved at such a rapid pace that today a consum...Lasīt vairāk
Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine, Steve Olson, Sarah H. Beachy, Claire F. Giammaria, Adam C. Berger
(Izdošanas datums: 06-Feb-2012, Hardback, Izdevniecība: National Academies Press, ISBN-13: 9780309384988)
Šī grāmata vairs netiek publicēta. Jums tiks paziņota lietotas grāmatas cena
The initial sequencing of the human genome, carried out by an international group of experts, took 13 years and 2.7 billion to complete. In the decade since that achievement, sequencing technology has evolved at such a rapid pace that today a...Lasīt vairāk
Ten years after the sequencing of the human genome, scientists have developed genetic tests that can predict a persons response to certain drugs, estimate the risk of developing Alzheimers disease, and make other predictions based on known links b...Lasīt vairāk
Despite the many basic research discoveries in genetics, relatively few gene-based treatments, drugs, or preventative measures have been developed. One way to bridge this gap may be for industry, academia, and government to develop partnerships that...Lasīt vairāk
Committee on Science, Technology, and Law, Forum on Drug Discovery, Development, and Translation, Roundtable on Translating Genomic-Based Research for Health, Board on Life Sciences, Board on Health Sciences Policy, Policy...
Under the aegis of the Institute of Medicine and National Research Councils Committee on Science, Technology, and Law Policy and Global Affairs, a workshop was held in August and September 2009 to bring together physicians, scientists, lawyers, ethi...Lasīt vairāk
Knowing ones genetic disposition to a variety of diseases, including common chronic diseases, can benefit both the individual and society at large. The IOMs Roundtable on Translating Genomic-Based Research for Health held a workshop on March 22, 2...Lasīt vairāk
