National Academies of Sciences, Engineering, and Medicine, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Board on Environmental Studies and Toxicology, Committee on Variability and Relevance of
As part of its core mission, the U.S. Environmental Protection Agency (EPA) is tasked with assessing the hazards and risks to human health from exposure to pollutants. While some pollutants are well studied, there are little or no data on the pot...Lasīt vairāk
National Academies of Sciences, Engineering, and Medicine, Division on Earth and Life Studies, Health and Medicine Division, Institute for Laboratory Animal Research, Board on Health Sciences Policy, Committee on the State
Nonhuman primates represent a small fraction of animals used in biomedical research, but they remain important research models due to their similarities to humans with respect to genetic makeup, anatomy, physiology, and behavior. Limitations in the...Lasīt vairāk
National Academies of Sciences, Engineering, and Medicine, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Teresa J. Sylvina
Research to advance understanding of the ecology and biology of wildlife species is more important than ever as the world confronts issues ranging from biodiversity loss to the emergence of zoonotic diseases. However, the current understanding of an...Lasīt vairāk
National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Board on Health Sciences Policy, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Committee on Assessment
For many years, laboratory dogs have served as important animal models for biomedical research that has advanced human health. Conducted at the request of the U.S. Department of Veterans Affairs (VA), this report assesses whether laboratory dogs are...Lasīt vairāk
National Academies of Sciences, Engineering, and Medicine, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Roundtable on Science and Welfare in Laboratory Animal Use, Lida Anestidou, Anne Frances Johnson
The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infe...Lasīt vairāk
National Academies of Sciences, Engineering, and Medicine, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Roundtable on Science and Welfare in Laboratory Animal Use, Lida Anestidou, Erin Hammers Forstag
Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine,...Lasīt vairāk
National Academies of Sciences, Engineering, and Medicine, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Roundtable on Science and Welfare in Laboratory Animal Use, Jenna Ogilvie, Lida Anestidou, Joe Alp
The surface of the human body and its mucous membranes are heavily colonized by microorganisms. Our understanding of the contributions that complex microbial communities make to health and disease is advancing rapidly. Most microbiome research to da...Lasīt vairāk
National Academies of Sciences, Engineering, and Medicine, Division on Earth and Life Studies, Health and Medicine Division, Institute for Laboratory Animal Research, Board on Earth Sciences and Resources, Board on Health S
The academic biomedical research community is a hub of employment, economic productivity, and scientific progress. Academic research institutions are drivers of economic development in their local and state economies and, by extension, the national...Lasīt vairāk
National Academies of Sciences Engineering and Medicine, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Roundtable on Science and Welfare in Laboratory Animal Use, Jenna Ogilvie, Lida Anestidou, Steven Olson
The obligation to treat animals used in research ethically and humanely extends beyond their lives in the laboratory to include their transportation from place to place. Yet transporting animals is a highly regulated and complex process that raises...Lasīt vairāk
National Academies of Sciences, Engineering, and Medicine, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Roundtable on Science and Welfare in Laboratory Animal Use, Lida Anestidou, Joe Alper
In order to better understand the critical issues pertaining to the concept of performance standards for laboratory animal use, the Institute for Laboratory Animal Research Roundtable on Science and Welfare in Laboratory Animal Use held a public wor...Lasīt vairāk
National Research Council, Institute of Medicine, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Policy and Global Affairs, Committee on Science, Technology, and Law, Board on Health Scienc
Animals are widely used in neuroscience research to explore biological mechanisms of nervous system function, to identify the genetic basis of disease states, and to provide models of human disorders and diseases for the development of new treatment...Lasīt vairāk
National Research Council, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Committee on Animal Models for Assessing Countermeasures to Bioterrorism Agents
The Transformational Medical Technologies (TMT) has been a unique component of the U.S. Department of Defense (DoD) medical biodefense efforts since 2006. Its mission is to advance countermeasure research and development in support of the broader go...Lasīt vairāk
The publication of research articles involving animal studies is central to many disciplines in science and biomedicine. Effective descriptions in such publications enable researchers to interpret the data, evaluate and replicate findings, and move...Lasīt vairāk
Animal research will play an essential role in efforts to meet increasing demands for global health care. Yet the animal research community faces the challenge of overcoming negative impressions that industry and academia engage in international col...Lasīt vairāk
Committee for the Update of the Guide for the Care and Use of Laboratory Animals, Institute for Laboratory Animal Research, Division on Earth and Life Studies, National Research Council
The National Academies Advisers to the National on Science, Engineering, and MedicineThe nation turns to the National Academies---National Academy of Sciences, National Academy of Engineering, Institute of Medicine, and National Research Coun...Lasīt vairāk
Committee for the Update of the Guide for the Care and Use of Laboratory Animals, Institute for Laboratory Animal Research, Division on Earth and Life Studies, National Research Council
(Izdošanas datums: 27-Dec-2010, Hardback, Izdevniecība: National Academies Press, ISBN-13: 9780309386296)
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A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. Th...Lasīt vairāk
National Research Council, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Committee on Recognition and Alleviation of Pain in Laboratory Animals
A committee with members from the US, Britain, and Canada has updated the 1992 National Research Council report Recognition and Alleviation of Pain and Distress in Laboratory Animals, breaking it into two publications in order to incorporate the scie...Lasīt vairāk
National Research Council, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Committee on Scientific and Humane Issues in the Use of Random Source Dogs and Cats in Research
The issues are more fraught with emotion than those regarding other laboratory research animals, and go back to the beginnings of both scientific research and the animal protection movement, because people feel very strongly about their pets. The com...Lasīt vairāk
National Research Council, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Committee on Recognition and Alleviation of Distress in Laboratory Animals
Providing updated guidelines based on current scientific research, this provides new, evidence-based techniques to use with animals in research, testing and education. These guidelines are based on a number of US and international standards that seek...Lasīt vairāk
National Research Council, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Board on Environmental Studies and Toxicology, Committee on Toxicity Testing and Assessment of Environmental Agents
Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S...Lasīt vairāk
