Principles of Nucleic Acid Structure, Second Edition, provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussions of X-ray crystallography, NMR, molecular...Lasīt vairāk
The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-useful regions, has led to a large number of studies aimed at exploitin...Lasīt vairāk
The study of G-quadruplexes has emerged in recent years as an important focus of research in nucleic acids. This is now a rapidly growing area, not least because of its potential as a novel approach to cancer therapeutics, and there is much curren...Lasīt vairāk
Specialists in cancer and pharmaceuticals, most in academic settings, look at basic principles of cancer drugs, methodology, drugs in the clinic, new agents, and the reality of cancer drugs in the clinic. They do not cover the fundamentals of cancer...Lasīt vairāk
New found interest in the chromosome G-quadruplexes has emerged as an important focus of research in nucleic acids and as a potential target for cancer therapeutics. Existing literature concerning nucleic acids concentrates on aspects of quadruple...Lasīt vairāk
Stephen Neidle, Simon Campbell, Henri Buc, Bianca Sclavi, Terence Strick, Andrew Travers, Marius Clore, G Muskhelishvili, David M J Lilley, Achilles Kapanidis...
Sērija : RSC Biomolecular Sciences
(Izdošanas datums: 10-Mar-2009, Hardback, Izdevniecība: Royal Society of Chemistry, ISBN-13: 9780854041343)
The cell can be viewed as a collection of protein machines and understanding these molecular machines requires sophisticated cooperation between cell biologists, geneticists, enzymologists, crystallographers, chemists and physicists. To observe the...Lasīt vairāk
Stephen Neidle, David M J Lilley, Marius Clore, Roderick E Hubbard
Sērija : RSC Biomolecular Sciences
(Izdošanas datums: 20-Feb-2009, Hardback, Izdevniecība: Royal Society of Chemistry, ISBN-13: 9781847559326)
Šī grāmata vairs netiek publicēta. Jums tiks paziņota lietotas grāmatas cena
The RSC Biomolecular Sciences Series is devoted to the coverage of the interface between the chemical and biological sciences, especially structural biology, chemical biology, bio- and chemo-informatics, drug discovery and development, chemical enzym...Lasīt vairāk
Šī grāmata vairs netiek publicēta. Jums tiks paziņota lietotas grāmatas cena
The ultimate source of information on the design of new anticancer agents, emphasising small molecules, this newest work covers recent notable successes resulting from the human genome and cancer genomics projects. These advances have provided inform...Lasīt vairāk
Šī grāmata vairs netiek publicēta. Jums tiks paziņota lietotas grāmatas cena
This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its...Lasīt vairāk
Stephen Neidle, Shankar Balasubramanian, William A Harrell Jr
Sērija : RSC Biomolecular Sciences
(Izdošanas datums: 20-Oct-2006, Hardback, Izdevniecība: Royal Society of Chemistry, ISBN-13: 9780854043743)
Guanine rich DNA has been known for decades to form unusual structures, although their biological relevance was little understood. Recent advances have demonstrated that quadruplex structures can play a role in gene expression and provide oppor...Lasīt vairāk
Šī grāmata vairs netiek publicēta. Jums tiks paziņota lietotas grāmatas cena
This is a comprehensive and clearly presented survey of the field of nucleic acid structure. It covers the major aspects of the structural biology and chemistry of nucleic acids (DNA and RNA), and is supported by a dedicated and free access website...Lasīt vairāk
(Izdošanas datums: 25-Mar-1999, Hardback, Izdevniecība: Oxford University Press, ISBN-13: 9780198500384)
Šī grāmata vairs netiek publicēta. Jums tiks paziņota lietotas grāmatas cena
The Oxford Handbook of Nucleic Acid Structure is a comprehensive reference on all aspects of nucleic acid structure, with particular emphasis on the results from X-ray crystallography and NMR studies. In nineteen chapters by leading experts, it descr...Lasīt vairāk
David J. Kerr, William John Gullick, Alexander Levitzki, Paul Workman, Garth Powis, Stephen Neidle, John S. Lazo, Alakananda Basu, Michael J. O. Wakelam, Fiona Jane Lofts...
Šī grāmata vairs netiek publicēta. Jums tiks paziņota lietotas grāmatas cena
This book covers a wide range of novel biochemical targets that appear to be the best leads in terms of designing novel targets for anticancer drug design. New Molecular Targets for Cancer Chemotherapy is a unique, multi-disciplinary effort, with int...Lasīt vairāk
Šī grāmata vairs netiek publicēta. Jums tiks paziņota lietotas grāmatas cena
Presents the fundamentals of DNA structure and the principles of DNA recognition by drugs and proteins. Summarizes the major methods used to study DNA structure, and describes structural features of DNA, including nonstandard forms. Covers DNA struct...Lasīt vairāk
This cutting-edge book surveys the current knowledge on the mode of action of the major classes of DNA-interactive antitumor agents, providing information that could be crucial for the discovery of new therapeutic substances. It is an important refer...Lasīt vairāk
Šī grāmata vairs netiek publicēta. Jums tiks paziņota lietotas grāmatas cena
Covers the cancer chemotherapy area as part of the Topics in Molecular and Structural Biology series. There is such a wealth of new material on anti-cancer drug design generated by workers in this area that it has been published in two volumes....Lasīt vairāk
Šī grāmata vairs netiek publicēta. Jums tiks paziņota lietotas grāmatas cena
This work covers the cancer chemotherapy area. It is part of the Topics in Molecular and Structural Biology series, which provides researchers in the biological and medical sciences with reviews of selected areas in molecular biology....Lasīt vairāk
